Structure	Catalog	Product Name	CAS	E3 Ligase	Target	Inquiry
	BPL-201733	3-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-5-isopropoxy-2-methylphenyl)piperidin-1-yl)-N-(8-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)octyl)propanamide	2417174-66-2	CRBN	ALK	Inquiry
Molecular Weight: 1070.71 Molecular Formula: C54H68ClN9O10S Density: 1.301±0.06 g/cm3 Description: It is an ALK degrader obtained by conjugation of LDK378 and CRBN E3 ubiquitin ligase ligand.
	BPL-201734	3-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-5-isopropoxy-2-methylphenyl)piperidin-1-yl)-N-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)ethoxy)ethyl)propanamide	2417174-68-4	CRBN	ALK	Inquiry
Molecular Weight: 1030.59 Molecular Formula: C50H60ClN9O11S Density: 1.350±0.06 g/cm3 Description: It is an ALK degrader obtained by conjugation of LDK378 and CRBN E3 ubiquitin ligase ligand.
	BPL-201735	3-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-5-isopropoxy-2-methylphenyl)piperidin-1-yl)-N-(2-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)ethoxy)ethoxy)ethyl)propanamide	2417174-69-5	CRBN	ALK	Inquiry
Molecular Weight: 1074.66 Molecular Formula: C52H64ClN9O12S Density: 1.339±0.06 g/cm3 Description: It is an ALK degrader obtained by conjugation of LDK378 and CRBN E3 ubiquitin ligase ligand.
	BPL-201736	3-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-5-isopropoxy-2-methylphenyl)piperidin-1-yl)-N-(1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-2-oxo-6,9,12-trioxa-3-azatetradecan-14-yl)propanamide	2417174-70-8	CRBN	ALK	Inquiry
Molecular Weight: 1118.71 Molecular Formula: C54H68ClN9O13S Density: 1.328±0.06 g/cm3 Description: It is an ALK degrader obtained by conjugation of LDK378 and CRBN E3 ubiquitin ligase ligand.
	BPL-201737	7-(4-(4-((9-Cyclopentyl-8-(phenylamino)-9H-purin-2-yl)amino)phenyl)piperazin-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)heptanamide		CRBN	EGFR EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 824.00 Molecular Formula: C46H53N11O4 Description: It is a potent small molecule PROTAC targeting mutant EGFR.
	BPL-201738	8-(4-(4-((9-Cyclopentyl-8-(phenylamino)-9H-purin-2-yl)amino)phenyl)piperazin-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)octanamide		CRBN	EGFR EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 838.03 Molecular Formula: C47H55N11O4 Description: It is a potent small molecule PROTAC targeting mutant EGFR.
	BPL-201739	PROTAC EGFR Degrader 4		VHL	EGFR e19d EGFR L858R/T790M EGFR	Inquiry
Molecular Weight: 995.31 Molecular Formula: C55H70N12O4S Density: 1.3±0.1 g/cm3 Description: It is a potent small molecule PROTAC targeting mutant EGFR.
	BPL-201740	(2S,4R)-1-((S)-2-(8-(4-(4-((9-Cyclopentyl-8-(phenylamino)-9H-purin-2-yl)amino)phenyl)piperazin-1-yl)octanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide		VHL	EGFR e19d EGFR L858R/T790M EGFR	Inquiry
Molecular Weight: 1009.34 Molecular Formula: C56H72N12O4S Description: It is a potent small molecule PROTAC targeting mutant EGFR.
	BPL-201741	2-((2-(2-(2-(4-(4-((9-Cyclopentyl-8-(phenylamino)-9H-purin-2-yl)amino)phenyl)piperazin-1-yl)ethoxy)ethoxy)ethyl)(methyl)amino)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)acetamide		CRBN	EGFR EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 899.07 Molecular Formula: C48H58N12O6 Description: It is a potent small molecule PROTAC targeting mutant EGFR.
	BPL-201742	14-(4-(4-((9-Cyclopentyl-8-(phenylamino)-9H-purin-2-yl)amino)phenyl)piperazin-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)-3-methyl-6,9,12-trioxa-3-azatetradecanamide		CRBN	EGFR e19d EGFR EGFR L858R/T790M	Inquiry
Molecular Weight: 943.12 Molecular Formula: C50H62N12O7 Description: It is a potent small molecule PROTAC targeting mutant EGFR.
	BPL-201743	17-(4-(4-((9-Cyclopentyl-8-(phenylamino)-9H-purin-2-yl)amino)phenyl)piperazin-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)-3-methyl-6,9,12,15-tetraoxa-3-azaheptadecanamide		CRBN	EGFR EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 987.18 Molecular Formula: C52H66N12O8 Description: It is a potent small molecule PROTAC targeting mutant EGFR.
	BPL-201744	(2S,4R)-1-((S)-2-((2-(2-(2-(4-(4-((9-Cyclopentyl-8-(phenylamino)-9H-purin-2-yl)amino)phenyl)piperazin-1-yl)ethoxy)ethoxy)ethyl)amino)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide		VHL	EGFR EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 999.30 Molecular Formula: C54H70N12O5S Description: It is a potent small molecule PROTAC targeting mutant EGFR.
	BPL-201745	(2S,4R)-1-((S)-2-(tert-Butyl)-14-(4-(4-((9-cyclopentyl-8-(phenylamino)-9H-purin-2-yl)amino)phenyl)piperazin-1-yl)-6,9,12-trioxa-3-azatetradecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide		VHL	EGFR EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1043.35 Molecular Formula: C56H74N12O6S Description: It is a potent small molecule PROTAC targeting mutant EGFR.
	BPL-201746	(2S,4R)-1-((S)-2-(tert-Butyl)-17-(4-(4-((9-cyclopentyl-8-(phenylamino)-9H-purin-2-yl)amino)phenyl)piperazin-1-yl)-6,9,12,15-tetraoxa-3-azaheptadecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide		VHL	EGFR EGFR e19d EGFR L858R/T790M	Inquiry
Molecular Weight: 1087.41 Molecular Formula: C58H78N12O7S Description: It is a potent small molecule PROTAC targeting mutant EGFR.
	BPL-201747	6-(5-Cyano-1H-pyrrolo[2,3-b]pyridin-1-yl)-N-(trans-4-((2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)ethyl)carbamoyl)cyclohexyl)-4-(isopropylamino)nicotinamide		CRBN	IRAK4	Inquiry
Molecular Weight: 802.85 Molecular Formula: C41H42N10O8 Description: It is a highly selective IRAK4 kinase inhibitor.
	BPL-201748	6-(5-Cyano-1H-pyrrolo[2,3-b]pyridin-1-yl)-N-(trans-4-((3-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)propyl)carbamoyl)cyclohexyl)-4-(isopropylamino)nicotinamide		CRBN	IRAK4	Inquiry
Molecular Weight: 816.88 Molecular Formula: C42H44N10O8 Description: It is a highly selective IRAK4 kinase inhibitor.
	BPL-201749	6-(5-Cyano-1H-pyrrolo[2,3-b]pyridin-1-yl)-N-(trans-4-((4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)carbamoyl)cyclohexyl)-4-(isopropylamino)nicotinamide		CRBN	IRAK4	Inquiry
Molecular Weight: 830.90 Molecular Formula: C43H46N10O8 Description: It is a highly selective IRAK4 kinase inhibitor.
	BPL-201750	6-(5-Cyano-1H-pyrrolo[2,3-b]pyridin-1-yl)-N-(trans-4-((5-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)pentyl)carbamoyl)cyclohexyl)-4-(isopropylamino)nicotinamide		CRBN	IRAK4	Inquiry
Molecular Weight: 844.93 Molecular Formula: C44H48N10O8 Description: It is a highly selective IRAK4 kinase inhibitor.
	BPL-201751	6-(5-Cyano-1H-pyrrolo[2,3-b]pyridin-1-yl)-N-(trans-4-((2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)ethoxy)ethyl)carbamoyl)cyclohexyl)-4-(isopropylamino)nicotinamide		CRBN	IRAK4	Inquiry
Molecular Weight: 846.90 Molecular Formula: C43H46N10O9 Description: It is a highly selective IRAK4 kinase inhibitor.
	BPL-201752	6-(5-Cyano-1H-pyrrolo[2,3-b]pyridin-1-yl)-N-(trans-4-((2-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)ethoxy)ethoxy)ethyl)carbamoyl)cyclohexyl)-4-(isopropylamino)nicotinamide		CRBN	IRAK4	Inquiry
Molecular Weight: 890.96 Molecular Formula: C45H50N10O10 Description: It is a highly selective IRAK4 kinase inhibitor.

PROTAC Library