PROTAC Library

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E3 Ligase
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Structure Catalog Product Name CAS E3 Ligase Target Inquiry
Pmd-PEG3-3C-Dab#1 BPL-201793 Pmd-PEG3-3C-Dab#1 2490499-31-3

CRBN

BRAF V600E

Inquiry

Molecular Weight: 1036.12

Molecular Formula: C48H52F3N9O10S2

Density: 1.419±0.06 g/cm3

Description: It is a PROTAC directed against BRAF mutant V600E.

Pmd-PEG4-3C-Dab#1 BPL-201794 Pmd-PEG4-3C-Dab#1 2490499-38-0

CRBN

BRAF V600E

Inquiry

Molecular Weight: 1080.18

Molecular Formula: C50H56F3N9O11S2

Density: 1.404±0.06 g/cm3

Description: It is a PROTAC directed against BRAF mutant V600E.

Pmd-PEG5-3C-Dab#1 BPL-201795 Pmd-PEG5-3C-Dab#1 2504050-85-3

CRBN

BRAF V600E

Inquiry

Molecular Weight: 1124.23

Molecular Formula: C52H60F3N9O12S2

Density: 1.390±0.06 g/cm3

Description: It is a PROTAC directed against BRAF mutant V600E.

Pmd-PEG6-3C-Dab#1 BPL-201796 Pmd-PEG6-3C-Dab#1 2504050-86-4

CRBN

BRAF V600E

Inquiry

Molecular Weight: 1168.28

Molecular Formula: C54H64F3N9O13S2

Density: 1.377±0.06 g/cm3

Description: It is a PROTAC directed against BRAF mutant V600E.

Pmd-PEG5-PEG5-Dab#1 BPL-201797 Pmd-PEG5-PEG5-Dab#1 2504050-87-5

CRBN

BRAF V600E

Inquiry

Molecular Weight: 1415.57

Molecular Formula: C65H85F3N10O18S2

Density: 1.334±0.06 g/cm3

Description: It is a PROTAC directed against BRAF mutant V600E.

Thd-1C-6C-Dab#1 BPL-201798 Thd-1C-6C-Dab#1 2490499-01-7

CRBN

BRAF V600E

Inquiry

Molecular Weight: 932.99

Molecular Formula: C44H43F3N8O8S2

Density: 1.437±0.06 g/cm3

Description: It is a PROTAC directed against BRAF mutant V600E.

VH-2C-6C-Dab#1 BPL-201799 VH-2C-6C-Dab#1 2504050-88-6

VHL

BRAF V600E

Inquiry

Molecular Weight: 1131.38

Molecular Formula: C55H65F3N10O7S3

Density: 1.333±0.06 g/cm3

Description: It is a PROTAC directed against BRAF mutant V600E.

VH-PEG4-Dab#2 BPL-201800 VH-PEG4-Dab#2 2504050-89-7

VHL

BRAF V600E

Inquiry

Molecular Weight: 1235.44

Molecular Formula: C58H69F3N10O11S3

Density: 1.366±0.06 g/cm3

Description: It is a PROTAC directed against BRAF mutant V600E.

Pmd-PEG3-Dab#2 BPL-201801 Pmd-PEG3-Dab#2 2490498-98-9

CRBN

BRAF V600E

Inquiry

Molecular Weight: 1006.05

Molecular Formula: C46H46F3N9O10S2

Density: 1.485±0.06 g/cm3

Description: It is a PROTAC directed against BRAF mutant V600E.

Pmd-PEG3-Az-C1-BI BPL-201802 Pmd-PEG3-Az-C1-BI 2490500-28-0

CRBN

BRAF V600E

Inquiry

Molecular Weight: 1070.19

Molecular Formula: C52H61F2N11O10S

Density: 1.48±0.1 g/cm3

Description: It is a PROTAC directed against BRAF mutant V600E.

Pmd-C1-Ph-C1-PPZ-C9-BI BPL-201803 Pmd-C1-Ph-C1-PPZ-C9-BI 2490499-98-2

CRBN

BRAF V600E

Inquiry

Molecular Weight: 1155.39

Molecular Formula: C61H72F2N12O7S

Density: 1.39±0.1 g/cm3

Description: It is a PROTAC directed against BRAF mutant V600E.

Pmd-PPZ-C9-BI BPL-201804 Pmd-PPZ-C9-BI 2490500-12-2

CRBN

BRAF V600E

Inquiry

Molecular Weight: 1036.22

Molecular Formula: C53H63F2N11O7S

Density: 1.43±0.1 g/cm3

Description: It is a PROTAC directed against BRAF mutant V600E.

Pmd-DODA-C1-BI BPL-201805 Pmd-DODA-C1-BI 2490502-63-9

CRBN

BRAF V600E

Inquiry

Molecular Weight: 1042.18

Molecular Formula: C51H61F2N11O9S

Density: 1.44±0.1 g/cm3

Description: It is a PROTAC directed against BRAF mutant V600E.

Pmd-PEG1-Trz-PEG2-BI BPL-201806 Pmd-PEG1-Trz-PEG2-BI 2504050-91-1

CRBN

BRAF V600E

Inquiry

Molecular Weight: 1082.16

Molecular Formula: C51H57F2N13O10S

Density: 1.51±0.1 g/cm3

Description: It is a PROTAC directed against BRAF mutant V600E.

Len(C)PEG4-BI BPL-201807 Len(C)PEG4-BI 2504050-92-2

CRBN

BRAF V600E

Inquiry

Molecular Weight: 1026.13

Molecular Formula: C51H57F2N9O10S

Density: 1.40±0.1 g/cm3

Description: It is a PROTAC directed against BRAF mutant V600E.

BC2P BPL-201808 BC2P

cIAP1

BTK

Inquiry

Molecular Weight: 1048.20

Molecular Formula: C56H67F2N9O9

Description: It is a ternary complex of BTK and cIAP1 protein degrader.

BCPip BPL-201809 BCPip

IAP

BTK

Inquiry

Molecular Weight: 983.13

Molecular Formula: C50H57F3N10O6S

Description: It is a ternary complex of BTK and cIAP1 protein degrader.

CPF1 BPL-201810 CPF1 2756741-88-3

CRBN

CDK2

Inquiry

Molecular Weight: 862.83

Molecular Formula: C37H36F2N12O9S

Density: 1.66±0.1 g/cm3

Description: It is a selective degrader of CDK2 for the differentiation treatment of AML.

CPS1 BPL-201811 CPS1 2756741-89-4

CRBN

CDK2

Inquiry

Molecular Weight: 846.91

Molecular Formula: C36H38N12O9S2

Density: 1.65±0.1 g/cm3

Description: It is a selective degrader of CDK2 for the differentiation treatment of AML.

CPS3 BPL-201812 CPS3 2756741-91-8

CRBN

CDK2

Inquiry

Molecular Weight: 935.02

Molecular Formula: C40H46N12O11S2

Density: 1.53±0.1 g/cm3

Description: It is a selective degrader of CDK2 for the differentiation treatment of AML.

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