Warhead Library - PROTAC® / BOC Sciences

Structure	Catalog	Product Name	CAS	Molecular Formula	Molecular Weight	Target	Inquiry
	BPL-100044	SMARCA-BD ligand 1 for Protac	1997319-92-2	C14H17N5O	271.32	PBRM1 SMARCA2 SMARCA4	Inquiry
	BPL-100045	4-bromo-7-methoxy-1-[[(2S)-5-oxopyrrolidin-2-yl]methoxy]isoquinoline-6-carboxamide	2363172-03-4	C16H16BrN3O4	394.22	IRAK4	Inquiry
	BPL-100046	290-R	2376726-16-6	C24H25ClN6O5S	545.00	SGK3	Inquiry
	BPL-100047	308-R	2376724-98-8	C23H23FN6O4S	498.52	SGK3	Inquiry
	BPL-100048	3-[5-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl]-6-methylpyridin-2-yl]-N-methylpropanamide	2639882-73-6	C24H24FN7O2	461.50	EED	Inquiry
	BPL-100049	IY-IY-TEG	1192378-55-4	C52H74N16O7	1035.26	TRKC	Inquiry
	BPL-100050	HG-7-85-01	1258391-13-7	C31H31F3N6O2S	608.68	BCR-ABL	Inquiry
Description: HG-7-85-01 is a type II ATP competitive inhibitor of wild-type and gatekeeper mutations forms of Bcr-Abl, PDGFRα, Kit, and Src kinases. HG-7-85-01 inhibits T315I mutant Bcr-Abl kinase, KDR and RET with IC50s of 3 nM, 20 nM and 30 nM.
	BPL-100051	ABL001 derivative	1492953-81-7	C22H20ClF2N5O4	491.87	BCR-ABL	Inquiry
	BPL-100052	7-[4-[(3,5-dichloropyridin-4-yl)amino]-7-methoxy-2-oxochromen-8-yl]oxyheptanoic acid	1001056-36-5	C22H22Cl2N2O6	481.32	PDE4	Inquiry
	BPL-100053	1-benzyl-4-(4-cyanophenyl)-2,5-dimethylpyrrole-3-carbonitrile	1354900-61-0	C21H17N3	311.38	AR	Inquiry
	BPL-100054	4-[4-[(4-fluorophenyl)methyl]-3,5-dimethylpyrazol-1-yl]-2-(trifluoromethyl)benzonitrile	1189135-45-2	C20H15F4N3	373.35	AR	Inquiry
	BPL-100055	2-chloro-4-[4-[2-(4-fluorophenyl)ethyl]-3,5-dimethylpyrazol-1-yl]benzonitrile	1189135-39-4	C20H17ClFN3	353.82	AR	Inquiry
	BPL-100056	3-chloro-4-[4-[(4-fluorophenyl)methyl]-3,5-dimethylpyrazol-1-yl]benzonitrile	1189135-53-2	C19H15ClFN3	339.80	AR	Inquiry
	BPL-100057	GSK-39	1714146-53-8	C22H25N3O5S2	475.57	BRD4 BRD7 BRD9	Inquiry
	BPL-100058	Methyl-[4-(6-methyl-benzothiazol-2-yl)-phenyl]-amine	95856-73-8	C15H14N2S	254.35	Htt	Inquiry
Description: N-Methyl-4-(6-methylbenzo[d]thiazol-2-yl)aniline is a useful research chemical for organic synthesis and other chemical processes.
	BPL-100059	TMX-2039	2488892-01-7	C17H20BrFN6O3S	487.34	AURKA CDK1 CDK12 CDK16 CDK17 CDK2 CDK4 CDK5 CDK6 CDK7 CDK9 MAPK10 MAPK8 MAPK9 RPS6KA1	Inquiry
	BPL-100060	TMX-3013	2488761-18-6	C17H14BrFN6O3S	481.30	AAK1 AURKA AURKB CDK1 CDK12 CDK16 CDK17 CDK2 CDK4 CDK5 CDK6 CDK7 CDK9 CLK1 FER GSK3A GSK-3beta IRAK3 MAP3K11 MAPK8 MAPK9 NUAK1 PRKAA1 PRKAA2 PTK2B RPS6KA1 RPS6KA3 STK33 STK38 TTK	Inquiry
	BPL-100061	TMX-3010	2488762-91-8	C18H16BrFN6O3S	495.32	AURKA AURKB CDK1 CDK2 CDK4 CDK5 CDK6 CDK7 CDK9 FAK MAPK8 MAPK9 RPS6KA1 RPS6KA3 STK33 TTK	Inquiry
	BPL-100062	TMX-3012	2488892-12-0	C18H16BrFN6O3S	495.32	AAK1 AURKA AURKB CDK1 CDK12 CDK17 CDK2 CDK4 CDK5 CDK6 CDK7 CDK9 CLK1 FAK FER GSK3A GSK-3beta IRAK3 MAP3K11 MAPK8 MAPK9 NEK1 NEK3 NEK4 NEK9 NUAK1 PRKAA1 PRKAA2 PTK2B RPS6KA1 RPS6KA3 RPS6KA4 STK33 STK35 STK38 TBK1 TEC TTK CDK16 Wee1	Inquiry
	BPL-100063	BETi-211	1995867-02-1	C26H29N7O3	487.55	BRD2 BRD3 BRD4	Inquiry