Warhead Library - PROTAC® / BOC Sciences

Structure	Catalog	Product Name	CAS	Molecular Formula	Molecular Weight	Target	Inquiry
	BPL-100084	3-nitrophenothiazine	1628-77-9	C12H8N2O2S	244.27	Alpha-syn	Inquiry
	BPL-100085	Deltazinone	894554-89-3	C27H31N5O2	457.57	PDEdelta	Inquiry
Description: Deltazinone is a highly potent and selective PDEδ inhibitor.
	BPL-100086	1-[4-[2-methyl-6-[[5-[(E)-2-(3-methylphenyl)ethenyl]-1,3-thiazol-2-yl]amino]pyrimidin-4-yl]piperazin-1-yl]hex-5-yn-1-one	2512848-38-1	C27H30N6OS	486.63	BCR-ABL T315I	Inquiry
	BPL-100087	4-[[(1S,5R)-8-azabicyclo[3.2.1]octan-3-yl]oxy]-2-chlorobenzonitrile		C14H15ClN2O	262.73	AR	Inquiry
	BPL-100088	VPC-14228	19983-28-9	C13H14N2OS	246.33	AR AR-V7	Inquiry
Description: VPC-14228 is a specific inhibitor of AR-DBD. It acts by inhibiting both Y594A and Q592A mutants, blocking the interaction of the AR with androgen response elements in the nucleus.
	BPL-100089	N-[3-[2-[4-(4-ethylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-7-yl]phenyl]methanesulfonamide	1644557-92-5	C25H28N6O2S2	508.66	AAK1 AURKA BMP2K CAMKK1 CDK1 CDK16 CDK17 CDK2 CDK4 CDK6 CDK7 EIF2AK2 EIF2AK4 FER GAK LATS1 LCK LIMK2 MAP3K11 MAPK6 MAPK8 MAPK9 MAPKAPK5 MARK2 MARK4 MKNK2 NEK9 PLK4 PTK2B RPS6KB1 SIK2 SNRK STK17A STK17B STK35 ULK1 ULK3 Wee1	Inquiry
	BPL-100090	9-cyclopentyl-2-N-[4-(4-methylpiperazin-1-yl)phenyl]-8-N-phenylpurine-2,8-diamine	1350544-90-9	C27H32N8	468.61	EGFR EGFR e19d EGFR L858R/T790M	Inquiry
	BPL-100091	2-[4-[[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl]amino]phenyl]acetonitrile	1636166-79-4	C19H20N8	360.43	AAK1 AURKA BMP2K GSK3A GSK-3beta	Inquiry
	BPL-100092	1-[3-(3-amino-1H-indazol-4-yl)phenyl]-3-(3-propan-2-ylphenyl)urea	1800110-27-3	C23H23N5O	385.47	VEGFR-2	Inquiry
	BPL-100093	2-[4-[[4-[(4,5-dimethyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]amino]phenyl]acetonitrile		C17H17N7	319.37	GSK3A GSK-3beta	Inquiry
	BPL-100093	2-[4-[[4-[(4-ethyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]amino]phenyl]acetonitrile		C17H17N7	319.37	GSK-3beta	Inquiry
	BPL-100094	[8-(4-Methanesulfonyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-(3-piperazin-1-yl-phenyl)-amine	1257706-63-0	C23H24N6O2S	448.55	JAK2	Inquiry
	BPL-100094	methyl 4-[[7-cyclopentyl-6-(dimethylcarbamoyl)pyrrolo[2,3-d]pyrimidin-2-yl]amino]benzoate	2541626-63-3	C22H25N5O3	407.47	CDK2 CDK4 CDK6 AAK1 AURKA JAK2	Inquiry
	BPL-100095	4-{[4-{[3-(methylsulfonyl)benzyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}benzamide	1073154-92-3	C20H18F3N5O3S	465.45	FAK	Inquiry
	BPL-100096	8-(3,5-difluoropyridin-2-yl)-N,15-dimethyl-4-(methylsulfonylmethyl)-14-oxo-8,12,15-triazatetracyclo[8.6.1.0^2,7.0^13,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaene-5-carboxamide		C24H21F2N5O4S	513.52	BRD4	Inquiry
	BPL-100097	4-[[(3aR,6aS)-5-amino-3a,6a-dimethyl-1,2,3,4,5,6-hexahydropentalen-2-yl]oxy]-2-chlorobenzonitrile		C17H21ClN2O	304.82	AR	Inquiry
	BPL-100098	[4-({4-[(5-Cyclopropyl-1h-Pyrazol-3-Yl)amino]pyrimidin-2-Yl}amino)phenyl]acetonitrile	1092559-18-6	C18H17N7	331.38	AAK1 AURKA AURKB BMP2K CDK9 EPHB2 GSK-3beta ITK LATS1 MAP4K2 NEK9 PAK4 PLK4 STK17B	Inquiry
	BPL-100099	3-[3-[4-(aminomethyl)phenyl]-5-phenylimidazo[4,5-b]pyridin-2-yl]pyridin-2-amine	1313881-75-2	C24H20N6	392.47	AKT1 AKT2 AKT3	Inquiry
	BPL-100100	methyl 4-[5-ethoxy-1-methyl-6-[[6-(trifluoromethyl)pyridine-2-carbonyl]amino]benzimidazol-2-yl]-2,2-dimethylbutanoate	2713973-42-1	C24H27F3N4O4	492.50	IRAK4	Inquiry
	BPL-100101	N8 Pyrido[2,3-d]pyrimidin-7-one deriv. 48	211247-20-0	C20H20N4O	332.41	AAK1 AURKA AURKB CDK6 CDK9 FGFR2 STK17A TTK	Inquiry