Warhead Library - PROTAC® / BOC Sciences

Structure	Catalog	Product Name	CAS	Molecular Formula	Molecular Weight	Target	Inquiry
	BPL-100022	[2-[[(5S,8S,10aR)-3-acetyl-8-[[(2S)-5-amino-1-(benzhydrylamino)-1,5-dioxopentan-2-yl]carbamoyl]-6-oxo-1,2,4,5,8,9,10,10a-octahydropyrrolo[1,2-a][1,5]diazocin-5-yl]carbamoyl]-1H-indol-5-yl] dihydrogen phosphate	2429877-33-6	C39H44N7O10P	801.79	STAT3	Inquiry
	BPL-100023	[2-[[(5S,8S,10aR)-3-acetyl-8-[[(2S)-5-amino-1-(benzhydrylamino)-1,5-dioxopentan-2-yl]carbamoyl]-6-oxo-1,2,4,5,8,9,10,10a-octahydropyrrolo[1,2-a][1,5]diazocin-5-yl]carbamoyl]-1H-indol-5-yl]methylphosphonic acid	2429877-36-9	C40H46N7O9P	799.82	STAT3	Inquiry
	BPL-100024	[[4-[(E)-4-[[(5S,8S,10aR)-3-acetyl-8-[[(2S)-5-amino-1-(benzhydrylamino)-1,5-dioxopentan-2-yl]carbamoyl]-6-oxo-1,2,4,5,8,9,10,10a-octahydropyrrolo[1,2-a][1,5]diazocin-5-yl]amino]-4-oxobut-2-en-2-yl]phenyl]-difluoromethyl]phosphonic acid	2429877-37-0	C41H47F2N6O9P	836.83	STAT3	Inquiry
	BPL-100026	6-(4-bromophenyl)sulfanyl-1-oxo-3-(3-oxobutylamino)phenalene-2-carbonitrile		C24H17BrN2O2S	477.38	BCL2 MCL1	Inquiry
	BPL-100027	Brigatinib A	1197958-90-9	C23H28ClN6O2P	486.94	ALK EGFR del19/T790M/C797S EGFR e19d EGFR L858R/T790M	Inquiry
Description: Brigatinib is an oral, potent and selective anaplastic lymphoma kinase (ALK) and c-ros oncogene 1 (ROS1) tyrosine kinase inhibitor.
	BPL-100028	Brigatinib B	2353496-74-7	C24H30ClN6O2P	500.97	ALK ALK G1202R	Inquiry
Description: Brigatinib is an oral, potent and selective anaplastic lymphoma kinase (ALK) and c-ros oncogene 1 (ROS1) tyrosine kinase inhibitor.
	BPL-100029	Brigatinib C	1197958-75-0	C28H37ClN7O2P	570.07	ALK ALK G1202R EGFR L858R/T790M FAK FER PTK2B PTK6 RPS6KA1	Inquiry
	BPL-100030	XTF-262	1429497-57-3	C29H31N7O3	525.61	EGFR EGFR L858R/T790M	Inquiry
	BPL-100031	BMS-1166-N-piperidine-COOH	2447066-00-2	C37H35ClN2O6	639.14	PD-L1	Inquiry
Description: BMS-1166-N-piperidine-COOH, the BMS-1166-based moiety, binds to E3 ligase ligand via a linker to form PROTAC PD-1/PD-L1 degrader-1 to degrade PD-1/PD-L1.
	BPL-100032	6,7,10-trimethoxy-2-phenylbenzo[h]chromen-4-one	1428646-04-1	C22H18O5	362.38	CYP1B1	Inquiry
	BPL-100033	7-Benzyl Guanine Monophosphate	130538-31-7	C17H21N5O8P+	454.36	eIF4E	Inquiry
	BPL-100034	P-Fluoro-7-Benzyl Guanine Monophosphate	952143-85-0	C17H20FN5O8P+	472.34	eIF4E	Inquiry
	BPL-100035	Bn7GDP	66761-16-8	C17H22N5O11P2+	534.33	eIF4E	Inquiry
	BPL-100036	7-(p-chlorobenzyl) GDP	238096-02-1	C17H21ClN5O11P2+	568.78	eIF4E	Inquiry
	BPL-100037	1-N-benzyl-4-N-[(4-chlorophenyl)methyl]-4-N-cyclopentyl-1-N-(piperidin-4-ylmethyl)benzene-1,4-disulfonamide	2088485-32-7	C31H38ClN3O4S2	616.23	PDEdelta	Inquiry
	BPL-100038	2-[8-(1,3-benzothiazol-2-ylcarbamoyl)-3,4-dihydro-1H-isoquinolin-2-yl]-5-[3-[2-fluoro-4-(3-piperazin-1-ylprop-1-ynyl)phenoxy]propyl]-1,3-thiazole-4-carboxylic acid	2143096-68-6	C37H35FN6O4S2	710.84	BCL-xL	Inquiry
	BPL-100040	2-methoxy-N-(1-methyl-2-oxobenzo[cd]indol-6-yl)benzenesulfonamide	2543542-54-5	C19H16N2O4S	368.41	BRD4	Inquiry
	BPL-100041	Pyrimidine 1	2561415-61-8	C16H15ClF2N6O	380.78	JAK1 JAK2	Inquiry
	BPL-100042	Quinoxaline 2	1092499-81-4	C33H36F2N4O5S	638.72	JAK1 JAK2	Inquiry
	BPL-100043	6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-methyl-4-phenyl-3,4-dihydroquinazolin-2-one	2133902-07-3	C20H19N3O2	333.39	BRD4	Inquiry