Bis-PEG21-NHS ester

 CAS No.: 2221948-98-5  Cat No.: BP-500825  Purity: >98.0% 4.5  

Bis-PEG21-NHS ester is a bifunctional PEG linker optimized for antibody-drug conjugates, providing extended hydrophilic spacing. Its dual NHS groups allow efficient amine coupling, facilitating stable and homogeneous conjugate formation in targeted therapies.

Bis-PEG21-NHS ester

Structure of 2221948-98-5

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Category
PROTAC Linker
Molecular Formula
C54H96N2O29
Molecular Weight
1237.34
Appearance
Solid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
>98.0%
Solubility
10 mm in DMSO
Appearance
Solid
ShelfLife
-20°C 3 years powder; -80°C 2 years in solvent
Storage
-20°C
Shipping
Room temperature
IUPACName
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Synonyms
Nhs-dpeg(tm)(21)-nhs; Bis-PEG21- NHS ester
InChI Key
UFBYDMNXKUEOPZ-UHFFFAOYSA-N
InChI
InChI=1S/C54H96N2O29/c57-49-1-2-50(58)55(49)84-53(61)5-7-63-9-11-65-13-15-67-17-19-69-21-23-71-25-27-73-29-31-75-33-35-77-37-39-79-41-43-81-45-47-83-48-46-82-44-42-80-40-38-78-36-34-76-32-30-74-28-26-72-24-22-70-20-18-68-16-14-66-12-10-64-8-6-54(62)85-56-51(59)3-4-52(56)60/h1-48H2
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON2C(=O)CCC2=O

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Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: Bis-PEG2-t-butyl ester | Aminooxy-PEG3-bromide | Acs-PEG4-propargyl | Acid-PEG3-SSPy | AcS-PEG5-OH | Azido-PEG4-NHS-ester | m-PEG3-AcS | DBCO-PEG4-acid | Mal-​PEG4-​propargyl | Propargyl-PEG3-azide | Bis-PEG21-NHS ester

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