Mal-PEG2-PFP - CAS 1807512-47-5

Mal-PEG2-PFP is a PEG linker containing maleimide and PFP moieties. Maleimide is thiol-reactive and reacts between pH 6.5 and 7.5 to form thiol ester bonds. PFP moiety is amine-reactive and is less susceptible to undergoing hydrolysis. The hydrophilic PEG linker increases the water solubility of a compound in aqueous media.

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Molecular Formula
C17H14F5NO6
Molecular Weight
423.29

Mal-PEG2-PFP

    • Specification
      • Purity
        ≥98%
        Solubility
        Soluble in DCM, DMF, DMSO
        Appearance
        Soild powder
        Storage
        Store at 2-8°C
        Shipping
        Room temperature
        IUPAC Name
        (2,3,4,5,6-pentafluorophenyl) 3-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]propanoate
        Synonyms
        Mal-PEG2-PFP ester; Perfluorophenyl 3-(2-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)propanoate; Perfluorophenyl 3-(2-(2-(2,5-dioxo-2H-pyrrol-1(5H)-yl)ethoxy)ethoxy)propanoate; Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester
    • Properties
      • Boiling Point
        493.1±45.0°C at 760 mmHg
        Density
        1.5±0.1 g/cm3
        InChI Key
        YMKYKJKJMZSGEN-UHFFFAOYSA-N
        InChI
        InChI=1S/C17H14F5NO6/c18-12-13(19)15(21)17(16(22)14(12)20)29-11(26)3-5-27-7-8-28-6-4-23-9(24)1-2-10(23)25/h1-2H,3-8H2
        Canonical SMILES
        C1=CC(=O)N(C1=O)CCOCCOCCC(=O)Oc2c(c(c(c(c2F)F)F)F)F
Bio Calculators
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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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