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Mal-PEG8-acid - CAS 1818294-46-0

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Mal-PEG8-acid is a non-cleavable 8-unit PEG ADC linker that is used in the synthesis of antibody conjugated drugs (ADCs). It is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules.

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Molecular Formula
C23H39NO12
Molecular Weight
521.56

Mal-PEG8-acid

    • Specification
      • Purity
        ≥95%
        Solubility
        Soluble in DCM, DMF, DMSO, Water
        Appearance
        Light Yellow or White Solid
        Storage
        Store at 2-8°C
        Shipping
        Room temperature in continental US; may vary elsewhere.
        IUPAC Name
        3-[2-[2-[2-[2-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
        Synonyms
        Mal-PEG8-CH2CH2COOH; Maleimide-PEG8-CH2CH2COOH; Mal-PEG8-COOH; Mal-PEG8-propionic acid; 1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid; 4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-; 3,6,9,12,15,18,21,24-Octaoxaheptacosan-27-oic acid, 1-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-
    • Properties
      • Boiling Point
        634.6±55.0°C at 760 mmHg
        Density
        1.2±0.1 g/cm3
        InChI Key
        KLZPPWOSICDUKQ-UHFFFAOYSA-N
        InChI
        InChI=1S/C23H39NO12/c25-21-1-2-22(26)24(21)4-6-30-8-10-32-12-14-34-16-18-36-20-19-35-17-15-33-13-11-31-9-7-29-5-3-23(27)28/h1-2H,3-20H2,(H,27,28)
        Canonical SMILES
        C1=CC(=O)N(C1=O)CCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O
    • Preparing Stock Solutions
      • ConcentrationVolumeMass1 mg5 mg10 mg
        1 mM1.9173 mL9.5866 mL19.1732 mL
        5 mM0.3835 mL1.9173 mL3.8346 mL
        10 mM0.1917 mL0.9587 mL1.9173 mL
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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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