Mal-PEG8-acid

 CAS No.: 1818294-46-0  Cat No.: BP-500095  Purity: ≥95% 4.5  

Mal-PEG8-acid is a non-cleavable 8-unit PEG ADC linker that is used in the synthesis of antibody conjugated drugs (ADCs). It is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules.

Mal-PEG8-acid

Structure of 1818294-46-0

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Category
PROTAC Linker
Molecular Formula
C23H39NO12
Molecular Weight
521.56
Appearance
Light Yellow or White Solid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DCM, DMF, DMSO, Water
Appearance
Light Yellow or White Solid
Storage
Store at 2-8°C
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
3-[2-[2-[2-[2-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Synonyms
Mal-PEG8-CH2CH2COOH; Maleimide-PEG8-CH2CH2COOH; Mal-PEG8-COOH; Mal-PEG8-propionic acid; 1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid; 4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-; 3,6,9,12,15,18,21,24-Octaoxaheptacosan-27-oic acid, 1-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-
Boiling Point
634.6±55.0°C at 760 mmHg
Density
1.2±0.1 g/cm3
InChI Key
KLZPPWOSICDUKQ-UHFFFAOYSA-N
InChI
InChI=1S/C23H39NO12/c25-21-1-2-22(26)24(21)4-6-30-8-10-32-12-14-34-16-18-36-20-19-35-17-15-33-13-11-31-9-7-29-5-3-23(27)28/h1-2H,3-20H2,(H,27,28)
Canonical SMILES
C1=CC(=O)N(C1=O)CCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O
ConcentrationVolumeMass1 mg5 mg10 mg
1 mM1.9173 mL9.5866 mL19.1732 mL
5 mM0.3835 mL1.9173 mL3.8346 mL
10 mM0.1917 mL0.9587 mL1.9173 mL

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It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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