webinar
Oct. 27-28, 2025, Boston, MA, USA - Booth 114.
Read More
webinar
August 17–21, 2025, Washington, DC, USA - Visit us at Booth 2230.
Read More

MS41 - CAS 2768610-97-3

Inquiry

MS41 is a highly potent and selective PROTAC degrader of eleven-nineteen leukemia (ENL) that recruits the von Hippel–Lindau (VHL) E3 ubiquitin ligase, with DC50 values of 3.50 nM (MV4;11), 2.84 nM (SEMK2), 3.03 nM (Jurkat), and 26.58 nM (KASUMI1). It effectively inhibits the growth of ENL-dependent leukemia cells by inducing G1 cell cycle arrest and increasing apoptosis, reduces the chromatin occupancy of ENL-associated transcription elongation machinery, and suppresses oncogenic gene expression and leukemia progression in both cellular and xenograft mouse models.

* Please be kindly noted that our services and products can only be used for research to organizations or companies and not intended for any clinical or individuals.

Molecular Formula
C56H70N8O9S
Molecular Weight
1031.3

MS41

    • Specification
      • Purity
        >95%
        Appearance
        White to off-white Solid
        Storage
        Store at -20 °C
        IUPAC Name
        5-[4-(dimethylcarbamoyl)-3-hydroxyphenyl]-N-[(1R)-6-[[10-[[(2S)-1-[(2S,4R)-4-hydroxy-2-[[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]carbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]amino]-10-oxodecyl]carbamoyl]-2,3-dihydro-1H-inden-1-yl]-1,2-oxazole-3-carboxamide
        Synonyms
        EX-A9896
    • Properties
      • Boiling Point
        1208.139±65.00 °C(Press: 760.00 Torr)(predicted)
        Density
        1.325±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
        InChI Key
        XPICNVKPGAOVBF-VCNVHFLLSA-N
        InChI
        InChI=1S/C56H70N8O9S/c1-33(35-16-19-37(20-17-35)49-34(2)58-32-74-49)59-53(70)45-29-40(65)31-64(45)55(72)50(56(3,4)5)61-48(67)15-13-11-9-8-10-12-14-26-57-51(68)39-21-18-36-23-25-43(42(36)27-39)60-52(69)44-30-47(73-62-44)38-22-24-41(46(66)28-38)54(71)63(6)7/h16-22,24,27-28,30,32-33,40,43,45,50,65-66H,8-15,23,25-26,29,31H2,1-7H3,(H,57,68)(H,59,70)(H,60,69)(H,61,67)/t33-,40+,43+,45-,50+/m0/s1
        Canonical SMILES
        CC1=C(SC=N1)C2=CC=C(C=C2)[C@H](C)NC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NC(=O)CCCCCCCCCNC(=O)C4=CC5=C(CC[C@H]5NC(=O)C6=NOC(=C6)C7=CC(=C(C=C7)C(=O)N(C)C)O)C=C4)O
Bio Calculators
Stock concentration: *
Desired final volume: *
Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

Calculate
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
g/mol
g
Related Products
Resources
Our Advantages
    • Advanced equipment and technique
    • Experienced scientific team
    • Highly reliable and reproducible result
    • Data analysis, detailed report with results and discussion
    • Quality one-stop service
BOC Sciences Support

Please contact us with any specific requirements and we will get back to you as soon as possible.


  • Verification code

We invite you to contact us at or through our contact form above for more information about our services and products.

USA
  • International:
  • US & Canada (Toll free):
  • Email:
  • Fax:
UK
  • Email:
Copyright © 2025 BOC Sciences. All Rights Reserved.
Inquiry Basket
Loading ......
Delete selectedGo to checkout