Pomalidomide 4'-PEG3-azide

 CAS No.: 2271036-46-3  Cat No.: BP-100121 4.5  

Pomalidomide 4'-PEG3-azide is a synthetic E3 ligase ligand-linker conjugate containing a cereblon ligand based on Pomalidomide and a PEG linker with terminal azide, which can be used for the synthesis of iRucaparib-TP3, an efficient PARP1 degradation agent.

Pomalidomide 4'-PEG3-azide

Structure of 2271036-46-3

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E3 Ligase Ligand-Linker Conjugate
Molecular Formula
C₂₁H₂₆N₆O₇
Molecular Weight
474.47

* For research and manufacturing use only. Not for human or clinical use.

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IUPACName
4-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethylamino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
InChI Key
IRPMZWZENVORCT-UHFFFAOYSA-N
InChI
1S/C21H26N6O7/c22-26-24-7-9-33-11-13-34-12-10-32-8-6-23-15-3-1-2-14-18(15)21(31)27(20(14)30)16-4-5-17(28)25-19(16)29/h1-3,16,23H,4-13H2,(H,25,28,29)
Canonical SMILES
[N-]=[N+]=NCCOCCOCCOCCNC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O
Pub Chem ID
150599703

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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: Pomalidomide-C2-COOH | Azido-PEG8-PFP ester | Pomalidomide-C6-NH2 | Pomalidomide-C8-COOH | Pomalidomide-PEG4-CO2H | 7-Octynoic Acid | (S,R,S)-AHPC-PEG6-NH2 hydrochloride | Leukotriene B | Mal-amido-PEG4-propionic acid | m-PEG6-2-methylacrylate | Pomalidomide 4'-PEG3-azide

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