Pomalidomide-C7-COOH

 CAS No.: 2225940-51-0  Cat No.: BP-100098 4.5  

Pomalidomide-C7-COOH is a synthetic E3 ligand-linker conjugate containing an E3 ligase ligand and a C7 alkyl linker with terminal carboxylic acid, which is an intermediate in the synthesis of PROTAC BCL-XL degradation agent.

Pomalidomide-C7-COOH

Structure of 2225940-51-0

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Category
E3 Ligase Ligand-Linker Conjugate
Molecular Formula
C₂₁H₂₅N₃O₆
Molecular Weight
415.44

* For research and manufacturing use only. Not for human or clinical use.

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Solubility
In DMSO: 50 mg/mL (120.35 mM; Need ultrasonic)<br/>In H2O: < 0.1 mg/mL (insoluble)
Storage
Powder, -20°C, 3 years; 4°C, 2 years; In solvent, -80°C, 6 months; -20°C, 1 month
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
8-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]octanoic acid
InChI Key
IJDAOSIFULSGHH-UHFFFAOYSA-N
InChI
1S/C21H25N3O6/c25-16-11-10-15(19(28)23-16)24-20(29)13-7-6-8-14(18(13)21(24)30)22-12-5-3-1-2-4-9-17(26)27/h6-8,15,22H,1-5,9-12H2,(H,26,27)(H,23,25,28)
Canonical SMILES
OC(CCCCCCCNC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O)=O
Pub Chem ID
134589383

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
g/mol
g
Historical Records: Pomalidomide-PEG6-butyl iodide | Bis-PEG5-acid | Pomalidomide-C7-COOH

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