Pomalidomide-PEG1-azide

 CAS No.: 2133360-04-8  Cat No.: BP-100033  Purity: ≥98% 4.5  

Pomalidomide-PEG1-azide is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal azide for click chemistry with a target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation.

Pomalidomide-PEG1-azide

Structure of 2133360-04-8

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Category
E3 Ligase Ligand-Linker Conjugate
Molecular Formula
C17H16N6O6
Molecular Weight
400.35

* For research and manufacturing use only. Not for human or clinical use.

SizePriceStockQuantity
50 mg $1299 In stock
100 mg $1990 In stock

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Purity
≥98%
ShelfLife
2 years
Storage
-20°C
IUPACName
2-(2-azidoethoxy)-N-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]acetamide
Synonyms
Pomalidomide-NH-PEG1-N3; 2-(2-Azidoethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide
InChI Key
SKTGGMFEGRISBY-UHFFFAOYSA-N
InChI
InChI=1S/C17H16N6O6/c18-22-19-6-7-29-8-13(25)20-10-3-1-2-9-14(10)17(28)23(16(9)27)11-4-5-12(24)21-15(11)26/h1-3,11H,4-8H2,(H,20,25)(H,21,24,26)
Canonical SMILES
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)COCCN=[N+]=[N-]

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: AZD-9291 | ATRA-hydroxyimino | t-Boc-N-amido-PEG2-amine | Thalidomide-NH-PEG1-NH2 hydrochloride | ABBV-744 | Pomalidomide-PEG2-NH2 dihydrochloride | (S,R,S)-AHPC-PEG2-NH2 hydrochloride | cIAP1 Ligand-Linker Conjugates 6 hydrochloride | (S,R,S)-AHPC-PEG1-azide | PROTAC K-Ras Degrader-1 | Pomalidomide-PEG1-azide

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