Propargyl-PEG3-acid

 CAS No.: 1347760-82-0  Cat No.: BP-501511  Purity: >98.0% 4.5  

Propargyl-PEG3-acid is an alkyne-functionalized ADC linker with a carboxyl terminus for amide coupling. Its PEG spacer enhances solubility and flexibility in antibody-drug conjugates, facilitating click chemistry-based bioconjugation strategies.

Propargyl-PEG3-acid

Structure of 1347760-82-0

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PROTAC Linker
Molecular Formula
C10H16O5
Molecular Weight
216.23
Appearance
Light yellow to brown clear liquid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
>98.0%
Solubility
Soluble in DCM, DMF, DMSO, Water
Appearance
Light yellow to brown clear liquid
ShelfLife
≥ 2 years
Storage
Store at -20°C, keep in dry and avoid sunlight
Shipping
Room temperature
IUPACName
3-[2-(2-prop-2-ynoxyethoxy)ethoxy]propanoic acid
Synonyms
3-(2-(2-(Prop-2-yn-1-yloxy)ethoxy)ethoxy)propanoic acid; Propyne-PEG2-CH2CH2COOH; Alkyne-PEG3-COOH; Propargyl-PEG3-COOH; Propargyl-PEG3-Carboxylic Acid; 3-[2-[2-(2-Propyn-1-yloxy)ethoxy]ethoxy]propanoic acid; Propanoic acid, 3-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-
Boiling Point
348.0±32.0 °C at 760 mmHg
Density
1.1±0.1 g/cm3
InChI Key
CJNSWLAJTZVSRB-UHFFFAOYSA-N
InChI
InChI=1S/C10H16O5/c1-2-4-13-6-8-15-9-7-14-5-3-10(11)12/h1H,3-9H2,(H,11,12)
Canonical SMILES
C#CCOCCOCCOCCC(=O)O

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It is commonly abbreviated as: C1V1 = C2V2

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Historical Records: S-acetyl-PEG12-alcohol | Bis-PEG10-acid | N-(Amino-PEG5)-N-bis(PEG4-acid) | BCN-PEG4-alkyne | TCO-PEG3-acid | SPDP-PEG4-COOH | Boc-Aminooxy-PEG3 | Mal-PEG24-acid | Mal-PEG5-acid | Fmoc-N-Amido-PEG2-alcohol | Propargyl-PEG3-acid

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