t-Boc-N-amido-PEG2-NHS ester

 CAS No.: 2183440-73-3  Cat No.: BP-501488  Purity: ≥95% 4.5  

t-Boc-N-amido-PEG2-NHS ester is a PEG linker containing NHS ester and Boc-protected amine moieties. The Boc group can be deprotected under mildly acidic conditions to form a free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.

t-Boc-N-amido-PEG2-NHS ester

Structure of 2183440-73-3

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Category
PROTAC Linker
Molecular Formula
C16H26N2O8
Molecular Weight
374.39
Appearance
White Solid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DCM, DMSO
Appearance
White Solid
Storage
Store at 2-8°C
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]propanoate
Synonyms
Boc-NH-PEG2-C2-NHS ester; 2,5-dioxopyrrolidin-1-yl 2,2-dimethyl-4-oxo-3,8,11-trioxa-5-azatetradecan-14-oate; BocNH-PEG2-CH2CH2COONHS; BOC-NH-PEG2-OCH2CH2COONHS Ester; 4,7,12-Trioxa-10-azatetradecanoic acid, 13,13-dimethyl-11-oxo-, 2,5-dioxo-1-pyrrolidinyl ester; 3-[2-(2-tert-Butoxycarbonylamino-ethoxy)-ethoxy]-propionic acid 2,5-dioxopyrrolidin-1-yl ester
Density
1.24±0.1 g/cm3 (Predicted)
InChI Key
FNZXIPYAXFROBS-UHFFFAOYSA-N
InChI
InChI=1S/C16H26N2O8/c1-16(2,3)25-15(22)17-7-9-24-11-10-23-8-6-14(21)26-18-12(19)4-5-13(18)20/h4-11H2,1-3H3,(H,17,22)
Canonical SMILES
CC(C)(C)OC(=O)NCCOCCOCCC(=O)ON1C(=O)CCC1=O

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Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: Bis-PEG5-t-butyl ester | N-(m-PEG4)-N'-(PEG3-Mal)-Cy5 | mPEG2-bromide | Thalidomide-5-(C6-amine) | Diethylene glycol 2-bromoethyl methyl ether | Br-PEG1-COOtBu | Acid-PEG2-t-butyl ester | Tetrazine-Ph-NHCO-PEG4-NH-Boc | DBCO-NHCO-C4-NHS ester | Propargyl-PEG2-N-bis(PEG2) | t-Boc-N-amido-PEG2-NHS ester

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