- Advanced equipment and technique
- Experienced scientific team
- Highly reliable and reproducible result
- Data analysis, detailed report with results and discussion
- Quality one-stop service

Tretinoin - CAS 302-79-4

Inquiry

Catalog Number	Size	Price	Stock	Quantity
BP-300092	5 g	$199	In stock

Add to cart

Tretinoin, a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells.

* Please be kindly noted that our services and products can only be used for research to organizations or companies and not intended for any clinical or individuals.

Molecular Formula

C20H28O2

Molecular Weight

300.43

Tretinoin

- Specification
  - Purity
    
    98%
    
    Solubility
    
    Soluble in Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
    
    Appearance
    
    Light Yellow to Yellow Solid
    
    Storage
    
    Store at -20°C, Under Inert at mosphere
    
    IUPAC Name
    
    (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
    
    Synonyms
    
    (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic Acid; All-trans Retinoic Acid; Isotretinoin EP Impurity A
- Properties
  - Boiling Point
    
    462.8±14.0°C at 760 mmHg
    
    Melting Point
    
    168-170°C
    
    Density
    
    1.011 g/cm3
    
    InChI Key
    
    SHGAZHPCJJPHSC-YCNIQYBTSA-N
    
    InChI
    
    InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
    
    Canonical SMILES
    
    CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
- Reference Reading
  - 1.Statistical optimization of tretinoin-loaded penetration-enhancer vesicles (PEV) for topical delivery.
    Bavarsad N1,2, Akhgari A3, Seifmanesh S4, Salimi A5,4, Rezaie A6. Daru. 2016 Feb 29;24:7. doi: 10.1186/s40199-016-0142-0.
    BACKGROUND: The aim of this study was to develop and optimize deformable liposome for topical delivery of tretinoin.
    2.Investigator-Blinded, Single-Center Study to Evaluate the Efficacy and Tolerability of a 4% Hydroquinone Skin Care System Plus 0.02% Tretinoin Cream in Mild-to-Moderate Melasma and Photodamage.
    Rendon M, Dryer L. J Drugs Dermatol. 2016 Apr 1;15(4):466-75.
    OBJECTIVE: To evaluate the treatment of mild-to-moderate epidermal melasma and photodamage using a 4% hydroquinone skin care system plus tretinoin 0.02% cream.
- Preparing Stock Solutions
  - ConcentrationVolumeMass 1 mg 5 mg 10 mg
    
    1 mM 3.3289 mL 16.6445 mL 33.2889 mL
    
    5 mM 0.6658 mL 3.3289 mL 6.6578 mL
    
    10 mM 0.3329 mL 1.6644 mL 3.3289 mL
    
    50 mM 0.0666 mL 0.3329 mL 0.6658 mL

ConcentrationVolumeMass	1 mg	5 mg	10 mg
1 mM	3.3289 mL	16.6445 mL	33.2889 mL
5 mM	0.6658 mL	3.3289 mL	6.6578 mL
10 mM	0.3329 mL	1.6644 mL	3.3289 mL
50 mM	0.0666 mL	0.3329 mL	0.6658 mL

Bio Calculators

Stock concentration: *

Desired final volume: *

Desired concentration: *

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C₁V₁ = C₂V₂

Calculate

* Total Molecular Weight:

g/mol

Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳

Formula weight: *

g/mol

Desired final volume: *

Desired concentration: *