Tretinoin

 CAS No.: 302-79-4  Cat No.: BP-300092  Purity: 98% 4.5  

Tretinoin, a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells.

Tretinoin

Structure of 302-79-4

Quality
Assurance

Worldwide
Delivery

24/7 Customer
Support
Category
Ligand for Target Protein
Molecular Formula
C20H28O2
Molecular Weight
300.43
Appearance
Light Yellow to Yellow Solid

* For research and manufacturing use only. Not for human or clinical use.

SizePriceStockQuantity
5 g $199 In stock

Looking for different specifications? Click to request a custom quote!

Capabilities & Facilities

  • mg to g scale for early stage;
  • CDMO and CMO support.
  • 24/7 customer service;
  • 100% quality assurance;
  • Efficient global delivery;
  • Over 95% customer satisfaction.
Popular Publications Citing BOC Sciences Products
Purity
98%
Solubility
Soluble in Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Appearance
Light Yellow to Yellow Solid
Storage
Store at -20°C, Under Inert at mosphere
IUPACName
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
Synonyms
(all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic Acid; All-trans Retinoic Acid; Isotretinoin EP Impurity A
Boiling Point
462.8±14.0°C at 760 mmHg
Melting Point
168-170°C
Density
1.011 g/cm3
InChI Key
SHGAZHPCJJPHSC-YCNIQYBTSA-N
InChI
InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
Canonical SMILES
CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
1.Statistical optimization of tretinoin-loaded penetration-enhancer vesicles (PEV) for topical delivery.
Bavarsad N1,2, Akhgari A3, Seifmanesh S4, Salimi A5,4, Rezaie A6. Daru. 2016 Feb 29;24:7. doi: 10.1186/s40199-016-0142-0.
BACKGROUND: The aim of this study was to develop and optimize deformable liposome for topical delivery of tretinoin.
2.Investigator-Blinded, Single-Center Study to Evaluate the Efficacy and Tolerability of a 4% Hydroquinone Skin Care System Plus 0.02% Tretinoin Cream in Mild-to-Moderate Melasma and Photodamage.
Rendon M, Dryer L. J Drugs Dermatol. 2016 Apr 1;15(4):466-75.
OBJECTIVE: To evaluate the treatment of mild-to-moderate epidermal melasma and photodamage using a 4% hydroquinone skin care system plus tretinoin 0.02% cream.
ConcentrationVolumeMass1 mg5 mg10 mg
1 mM3.3289 mL16.6445 mL33.2889 mL
5 mM0.6658 mL3.3289 mL6.6578 mL
10 mM0.3329 mL1.6644 mL3.3289 mL
50 mM0.0666 mL0.3329 mL0.6658 mL

Stock concentration: *
Desired final volume: *
Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
g

Related Product Recommendations

BOC Sciences Support

Please contact us with any specific requirements and we will get back to you as soon as possible.


  • Verification code

We invite you to contact us at or through our contact form above for more information about our services and products.

USA
  • International:
  • US & Canada (Toll free):
  • Email:
  • Fax:
UK
Germany
Inquiry Basket