2,5-dioxopyrrolidin-1-yl 1-(bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10-trioxa-4-azatridecan-13-oate
2,5-dioxopyrrolidin-1-yl 1-(bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10-trioxa-4-azatridecan-13-oate is a PEG-containing synthetic building block used to introduce flexible, hydrophilic spacing into multistep molecular and bioconjugation designs. Depending on the derivative, the terminal group may be protected or available for further conversion to an amine, ester, aldehyde, alkyne, or other functional handle. The PEG segment can help tune molecular reach and hydrophilicity while providing a modular connection between functional components. Selection of activation, deprotection, and coupling conditions should be guided by the terminal groups present and the chemistry planned for the next synthetic step.
Structure of 2243565-12-8
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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
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