2,5-dioxopyrrolidin-1-yl 1-(bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10-trioxa-4-azatridecan-13-oate

 CAS No.: 2243565-12-8  Cat No.: BP-501225  Purity: 98% 4.5  

2,5-dioxopyrrolidin-1-yl 1-(bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10-trioxa-4-azatridecan-13-oate is a PEG-containing synthetic building block used to introduce flexible, hydrophilic spacing into multistep molecular and bioconjugation designs. Depending on the derivative, the terminal group may be protected or available for further conversion to an amine, ester, aldehyde, alkyne, or other functional handle. The PEG segment can help tune molecular reach and hydrophilicity while providing a modular connection between functional components. Selection of activation, deprotection, and coupling conditions should be guided by the terminal groups present and the chemistry planned for the next synthetic step.

2,5-dioxopyrrolidin-1-yl 1-(bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10-trioxa-4-azatridecan-13-oate

Structure of 2243565-12-8

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PROTAC Linker
Molecular Formula
C22H30N2O8
Molecular Weight
450.48
Appearance
Soild powder

* For research and manufacturing use only. Not for human or clinical use.

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Purity
98%
Solubility
DMSO, DCM, DMF
Appearance
Soild powder
Storage
-20°C
Shipping
Room temperature, or blue ice upon request.
IUPACName
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-(9-bicyclo[6.1.0]non-4-ynylmethoxycarbonylamino)ethoxy]ethoxy]propanoate
Synonyms
endo-BCN-PEG2-OSu; endo-BCN-PEG2-NHS ester
InChI Key
HVVMKCPRACMDSI-UHFFFAOYSA-N
InChI
InChI=1S/C22H30N2O8/c25-19-7-8-20(26)24(19)32-21(27)9-11-29-13-14-30-12-10-23-22(28)31-15-18-16-5-3-1-2-4-6-17(16)18/h16-18H,3-15H2,(H,23,28)
SMILES
C1CC2C(C2COC(=O)NCCOCCOCCC(=O)ON3C(=O)CCC3=O)CCC#C1

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Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
g

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