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Aminooxy-PEG12-amido-PEG12-(mPEG11)3

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Aminooxy-PEG12-amido-PEG12-(mPEG11)3 is a densely branched, monodisperse PEG construct engineered to boost the hydrodynamic volume and circulation half-life of peptides and proteins while simultaneously minimizing their immunogenicity. Its architecture features a linear, aminooxy-terminated “tail”, a trifurcated tris core that introduces branching, and three methoxy-capped dPEG arms. Each numerical suffix indicates the precise count of repeating ethylene-oxide units in the corresponding segment. The reagent is fully hydrophilic, non-immunogenic, and exhibits a single, discrete molecular weight. The terminal aminooxy group selectively couples with aldehydes or ketones under mild conditions to yield stable oxime linkages.

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Molecular Formula
C136H270N6O66
Molecular Weight
3045.6

Aminooxy-PEG12-amido-PEG12-(mPEG11)3

    • Specification
      • Purity
        >90%
        Appearance
        Solid or viscous liquid
        IUPAC Name
        3-(2-aminooxyethoxy)-N-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[3-[[1,3-bis[3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethylamino]-3-oxopropoxy]-2-[[3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethylamino]-3-oxopropoxy]methyl]propan-2-yl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]propanamide
        Synonyms
        Aminooxy-dPEG(R)12-amido-dPEG(R)12-(m-dPEG(R)11)3
    • Properties
      • InChI Key
        XSNZUIBRYKKHCJ-UHFFFAOYSA-N
        InChI
        InChI=1S/C114H226N6O55/c1-126-22-25-135-38-41-143-54-57-151-70-73-159-86-89-167-98-93-163-83-78-156-67-62-148-51-46-140-35-30-132-19-10-117-110(122)5-15-172-106-114(107-173-16-6-111(123)118-11-20-133-31-36-141-47-52-149-63-68-157-79-84-164-94-99-168-90-87-160-74-71-152-58-55-144-42-39-136-26-23-127-2,108-174-17-7-112(124)119-12-21-134-32-37-142-48-53-150-64-69-158-80-85-165-95-100-169-91-88-161-75-72-153-59-56-145-43-40-137-27-24-128-3)120-113(125)8-14-129-28-33-138-44-49-146-60-65-154-76-81-162-92-97-170-102-103-171-101-96-166-82-77-155-66-61-147-50-45-139-34-29-131-18-9-116-109(121)4-13-130-104-105-175-115/h4-108,115H2,1-3H3,(H,116,121)(H,117,122)(H,118,123)(H,119,124)(H,120,125)
        Canonical SMILES
        COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCOCC(COCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)(COCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCOCCON
Bio Calculators
Stock concentration: *
Desired final volume: *
Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
g/mol
g
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