Azido-PEG7-amine

 CAS No.: 1333154-77-0  Cat No.: BP-500027  Purity: ≥95% 4.5  

Azido-PEG7-amine is a bifunctional ADC linker with azide and amine termini, ideal for click chemistry and amide coupling. The PEG7 chain improves pharmacokinetics and reduces aggregation of conjugates.

Azido-PEG7-amine

Structure of 1333154-77-0

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Category
PROTAC Linker
Molecular Formula
C16H34N4O7
Molecular Weight
394.46
Appearance
Light Yellow to Light Beige Oily Matter

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in Chloroform (Slightly), Methanol (Slightly)
Appearance
Light Yellow to Light Beige Oily Matter
Storage
Store at 2-8°C under inert atmosphere
Shipping
Room temperature
IUPACName
2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
Synonyms
Amino-PEG7-azide; 23-azido-3,6,9,12,15,18,21-heptaoxatricosan-1-amine; Azido-PEG7-NH2; N3-PEG7-CH2CH2NH2; N3-PEG7-NH2
InChI Key
VZKXLNRXAFTBOW-UHFFFAOYSA-N
InChI
InChI=1S/C16H34N4O7/c17-1-3-21-5-7-23-9-11-25-13-15-27-16-14-26-12-10-24-8-6-22-4-2-19-20-18/h1-17H2
Canonical SMILES
C(COCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])N
Biological Activity
Azido-PEG7-amine is a non-cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
ConcentrationVolumeMass1 mg5 mg10 mg
1 mM2.5351 mL12.6756 mL25.3511 mL
5 mM0.5070 mL2.5351 mL5.0702 mL
10 mM0.2535 mL1.2676 mL2.5351 mL

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: Pomalidomide-PEG6-butyl iodide | Bis-PEG5-acid | Pomalidomide-C7-COOH | Benzyl-PEG2-azide | Azido-PEG7-amine

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