Bis-PEG25-NHS ester

 CAS No.: 2221948-96-3  Cat No.: BP-501545  Purity: >98.0% 4.5  

Bis-PEG25-NHS ester features a long PEG spacer with dual NHS esters, widely used in ADC linker design for hydrophilic and flexible bioconjugation. This linker improves solubility and reduces aggregation, enhancing the therapeutic index of antibody-drug conjugates.

Bis-PEG25-NHS ester

Structure of 2221948-96-3

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Category
PROTAC Linker
Molecular Formula
C14H16N2O10
Molecular Weight
372.28
Appearance
Solid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
>98.0%
Solubility
10 mm in DMSO
Appearance
Solid
ShelfLife
-20°C 3 years powder; -80°C 2 years in solvent
Storage
-20°C
Shipping
Room temperature
IUPACName
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Synonyms
NHS-PEG24-NHS
InChI Key
JPTYKIPGEDAOCK-UHFFFAOYSA-N
InChI
InChI=1S/C62H112N2O33/c65-57-1-2-58(66)63(57)96-61(69)5-7-71-9-11-73-13-15-75-17-19-77-21-23-79-25-27-81-29-31-83-33-35-85-37-39-87-41-43-89-45-47-91-49-51-93-53-55-95-56-54-94-52-50-92-48-46-90-44-42-88-40-38-86-36-34-84-32-30-82-28-26-80-24-22-78-20-18-76-16-14-74-12-10-72-8-6-62(70)97-64-59(67)3-4-60(64)68/h1-56H2
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON2C(=O)CCC2=O

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Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: Carboxyrhodamine 110-PEG4-alkyne | N-(Amino-PEG3)-N-bis(PEG3-Boc) | TCO-PEG3-amine | Azido-PEG7-alcohol | Tri-(PEG1-C2-acid) | Aminooxy-PEG3-C2-thiol | Azido-PEG3-Sulfone-PEG4-Boc | N-Benzyl-N-bis-PEG2 | m-PEG21-acid | Bis-PEG25-NHS ester

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