CCT367766 formic is an orally active protein degrader and a Cereblon-based pirin-targeting PROTAC (PDP or PROTAC). It reduces pirin protein expression at low concentrations. It shows moderate affinity for the CRBN-DDB1 complex with an IC50 of 490 nM. CCT367766 formic has good affinity for recombinant pirin and CRBN with Kd values of 55 nM and 120 nM, respectively. It serves as a useful chemical tool for studying unexplored proteins.
* For research and manufacturing use only. Not for human or clinical use.
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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
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