Cbz-N-amido-PEG2-acetic acid
Cbz-NH-PEG2-CH2COOH is a polyethylene glycol (PEG)-based PROTAC linker. Cbz-NH-PEG2-CH2COOH can be used in the synthesis of a series of PROTACs.
Structure of 165454-06-8
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Category
PROTAC Linker
Molecular Formula
C₁₄H₁₉NO₆
Molecular Weight
297.30
* For research and manufacturing use only. Not for human or clinical use.
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Storage
Pure form, -20°C, 3 years; 4°C, 2 years; In solvent, -80°C, 6 months; -20°C, 1 month
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
2-[2-[2-(phenylmethoxycarbonylamino)ethoxy]ethoxy]acetic acid
Synonyms
CBZ-NH-PEG2-CH2COOH; Cbz-8-amino-3,6-dioxaoctanoic acid DCHA; 3-Oxo-1-phenyl-2,7,10-trioxa-4-azadodecan-12-oic acid; 10-oxo-12-phenyl-3,6,11-Trioxa-9-azadodecanoic acid
Boiling Point
506.6±45.0 °C at 760 mmHg
Density
1.2±0.1 g/cm3
InChI Key
GWUWSVXMAZFFNT-UHFFFAOYSA-N
InChI
InChI=1S/C14H19NO6/c16-13(17)11-20-9-8-19-7-6-15-14(18)21-10-12-4-2-1-3-5-12/h1-5H,6-11H2,(H,15,18)(H,16,17)
SMILES
C1=CC=C(C=C1)COC(=O)NCCOCCOCC(=O)O
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
Historical Records: Tetrazine-Ph-NHS ester | (S,R,S)-AHPC-PEG2-NH2 hydrochloride | N-(Propargyl-PEG4)-N-bis(PEG4-acid) | N-(m-PEG4)-N'-(Biotin-PEG2-amido-PEG4)-Cy5 | 1,3,4,6-Tetra-O-acetyl-N-azidoacetylmannosamine | Biotin-PEG4-amino-t-Bu-DADPS-C6-azide | N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 | 10-(tert-Butoxy)-10-oxodecanoic NHS ester | Dabrafenib | t-Boc-N-amido-PEG10-amine | Cbz-N-amido-PEG2-acetic acid
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