DBCO-NH-PEG4-amine

 CAS No.: 1255942-08-5  Cat No.: BP-501269  Purity: ≥95% 4.5  

DBCO-NH-PEG4-amine is a versatile ADC linker featuring a dibenzocyclooctyne group for copper-free click chemistry. Ideal for antibody-drug conjugate development, it enables efficient bioconjugation via strain-promoted azide-alkyne cycloaddition (SPAAC), enhancing stability and hydrophilicity in targeted drug delivery systems.

DBCO-NH-PEG4-amine

Structure of 1255942-08-5

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Category
PROTAC Linker
Molecular Formula
C29H37N3O6
Molecular Weight
523.62
Appearance
Light yellow oil

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
10 mm in DMSO
Appearance
Light yellow oil
Application
Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.
ShelfLife
0-4°C for short term (days to weeks), or -20°C for long term (months).
Storage
Store at -5°C,keep in dry and avoid sunlight.
Shipping
Room temperature, or blue ice upon request.
IUPACName
3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-N-[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]propanamide
Synonyms
DBCO-PEG4-NH2;DBCO-NHCO-PEG4-amine TFA salt;DBCO-PEG4-amine;Azadibenzocyclooctyne-PEG4 amine; DBCO-PEG4 amine
Boiling Point
784.1±60.0 °C at 760 mmHg
Density
1.2±0.1 g/cm3
InChI Key
KTIOBJVNCOFWCL-UHFFFAOYSA-N
InChI
InChI=1S/C29H37N3O6/c30-13-16-36-18-20-38-22-21-37-19-17-35-15-12-28(33)31-14-11-29(34)32-23-26-7-2-1-5-24(26)9-10-25-6-3-4-8-27(25)32/h1-8H,11-23,30H2,(H,31,33)
Canonical SMILES
C1C2=CC=CC=C2C#CC3=CC=CC=C3N1C(=O)CCNC(=O)CCOCCOCCOCCOCCN

Stock concentration: *
Desired final volume: *
Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
g/mol
g
Historical Records: Propargyl-PEG3-OCH2-Boc | MS-PEG4-THP | S-Acetyl-PEG3-azide | Benzyl-PEG2-CH2-Boc | Bromo-PEG5-phosphonic acid | mPEG4-aldehyde | Mal-NH-PEG3-NH-Mal | Amino-PEG2-propionic acid | Aminooxy-PEG2-azide | Azido-PEG3-t-butyl ester | DBCO-NH-PEG4-amine

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