Fmoc-N-amido-PEG8-propionic acid

 CAS No.: 756526-02-0  Cat No.: BP-500978  Purity: ≥95% 4.5  

Fmoc-N-amido-PEG8-propionic acid combines Fmoc protective groups with an 8-unit PEG spacer, optimizing ADC linker stability and solubility. This intermediate supports precise antibody conjugation and controlled drug release in targeted antibody-drug conjugates.

Fmoc-N-amido-PEG8-propionic acid

Structure of 756526-02-0

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Molecular Formula
C34H49NO12
Molecular Weight
663.75
Appearance
Colourless to pale yellow liquid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DMSO (10 mm)
Appearance
Colourless to pale yellow liquid
Storage
Store at -20°C, keep in dry and avoid sunlight
Shipping
Room temperature, or blue ice upon request.
IUPACName
3-[2-[2-[2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Synonyms
Fmoc-N-amido-PEG8-acid; 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28-nonaoxa-4-azahentriacontan-31-oic acid; Fmoc-NH-PEG8-CH2CH2COOH; 1-(Fmoc-amino)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic Acid; Fmoc-PEG8-propionic acid; 5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid, 1-(9-fluren-9-ylmethyl)ester; 2,7,10,13,16,19,22,25,28-Nonaoxa-4-azahentriacontan-31-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
Boiling Point
781.1±60.0 °C at 760 mmHg
Density
1.190±0.06 g/cm3
InChI Key
VYXGUCLTEWCVRY-UHFFFAOYSA-N
InChI
InChI=1S/C34H49NO12/c36-33(37)9-11-39-13-15-41-17-19-43-21-23-45-25-26-46-24-22-44-20-18-42-16-14-40-12-10-35-34(38)47-27-32-30-7-3-1-5-28(30)29-6-2-4-8-31(29)32/h1-8,32H,9-27H2,(H,35,38)(H,36,37)
Canonical SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: mPEG11-bromide | Fmoc-N-amido-PEG24-propionic acid | N-Boc-N-bis(PEG3-azide) | t-Boc-N-amido-PEG11-alcohol | Boc-NH-PEG5-Ms | Pyrene-PEG5-propargyl | N-Boc-PEG23-bromide | Boc-NH-PEG9-propargyl | m-PEG7-Ms | DBCO-NHCO-PEG2-NHS ester | Fmoc-N-amido-PEG8-propionic acid

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