Fmoc-NH-PEG2-NHS ester - CAS 1807534-85-5

Fmoc-NH-PEG2-NHS ester is a PEG linker containing a Fmoc-protected amine and an NHS ester. The Fmoc group can be deprotected under the basic conditions to obtain the free amine which can be used for further conjugations. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.

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Molecular Formula
C26H28N2O8
Molecular Weight
496.51

Fmoc-NH-PEG2-NHS ester

    • Specification
      • Purity
        ≥95%
        Solubility
        Soluble in DMSO
        Appearance
        Colorless Oily Matter
        Storage
        Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
        Shipping
        Room temperature in continental US; may vary elsewhere.
        IUPAC Name
        (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]propanoate
        Synonyms
        Fmoc-PEG2-NHS ester; Fmoc-PEG2-C2-NHS ester; Fmoc-NH-PEG2-NHS; FmocNH-PEG2-CH2CH2COONHS; Fmoc-PEG2-CH2CH2-NHS ester; Fmoc-N-amido-PEG2-NHS ester; 9H-Fluoren-9-ylmethyl [2-(2-{3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethoxy)ethyl]carbamate; Carbamic acid, N-[2-[2-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy]ethoxy]ethyl]-, 9H-fluoren-9-ylmethyl ester
    • Properties
      • Density
        1.4±0.1 g/cm3
        InChI Key
        MLMVUZTWJNGUEN-UHFFFAOYSA-N
        InChI
        InChI=1S/C26H28N2O8/c29-23-9-10-24(30)28(23)36-25(31)11-13-33-15-16-34-14-12-27-26(32)35-17-22-20-7-3-1-5-18(20)19-6-2-4-8-21(19)22/h1-8,22H,9-17H2,(H,27,32)
        Canonical SMILES
        C1CC(=O)N(C1=O)OC(=O)CCOCCOCCNC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
Bio Calculators
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L

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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