t-Boc-N-amido-PEG4-acetic acid

 CAS No.: 876345-13-0  Cat No.: BP-501613  Purity: 98% 4.5  

BocNH-PEG4-acid is a cleavable ADC linker used as a linker for antibody-drug conjugates and a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

t-Boc-N-amido-PEG4-acetic acid

Structure of 876345-13-0

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Category
PROTAC Linker
Molecular Formula
C15H29NO8
Molecular Weight
351.39
Appearance
Solid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
98%
Solubility
10 mm in DMSO
Appearance
Solid
Storage
Store at -20°C
Shipping
Room temperature
IUPACName
2-[2-[2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
Synonyms
2,2-Dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azanonadecan-19-oic acid; t-Boc-N-amido-PEG4-CH2CO2H; BocNH-PEG4-CH2COOH; 14-(Boc-amino)-3,6,9,12-tetraoxatetradecan-1-oic Acid
Boiling Point
493.6±40.0 °C at 760 mmHg
Density
1.138±0.06 g/cm3
InChI Key
SHMYENBXRNPSOG-UHFFFAOYSA-N
InChI
InChI=1S/C15H29NO8/c1-15(2,3)24-14(19)16-4-5-20-6-7-21-8-9-22-10-11-23-12-13(17)18/h4-12H2,1-3H3,(H,16,19)(H,17,18)
Canonical SMILES
CC(C)(C)OC(=O)NCCOCCOCCOCCOCC(=O)O
Biological Activity
Boc-NH-PEG4-CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC)[1]

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
g

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