THP-PEG4-alcohol
THP-PEG4-OH is a polyethylene glycol (PEG)-based PROTAC linker. THP-PEG4-OH can be used in the synthesis of a series of PROTACs.
Structure of 128660-97-9
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Category
PROTAC Linker
Molecular Formula
C13H26O6
Molecular Weight
278.34
Related CAS
92417-25-9 (polymer) 301295-36-3 (polymer)
Appearance
Colorless Oily Liquid
* For research and manufacturing use only. Not for human or clinical use.
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Purity
≥95%
Appearance
Colorless Oily Liquid
Storage
Store at 2-8°C
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
2-[2-[2-[2-(oxan-2-yloxy)ethoxy]ethoxy]ethoxy]ethanol
Synonyms
OH-PEG4-THP; THP-PEG5; HO-PEG4-THP; 2-(2-{2-[2-(Tetrahydropyran-2-yloxy)-ethoxy]-ethoxy}-ethoxy)-ethanol; 2-(2-(2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethan-1-ol; 2-[2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]-ethoxy]ethanol; Tetraethylene glycol mono-tetrahydropyran-2-yl ether; 2-[(11-Hydroxy-3,6,9-trioxaundecane-1-yl)oxy]tetrahydro-2H-pyran; Ethanol, 2-[2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]ethoxy]-; THP-PEG4-OH
Boiling Point
394.0±42.0 °C at 760 mmHg
Density
1.1±0.1 g/cm3
InChI Key
XUTYVMRXVARJFT-UHFFFAOYSA-N
InChI
InChI=1S/C13H26O6/c14-4-6-15-7-8-16-9-10-17-11-12-19-13-3-1-2-5-18-13/h13-14H,1-12H2
SMILES
C1CCOC(C1)OCCOCCOCCOCCO
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
Historical Records: 2,5,8,11,14,17-Hexaoxa-19-nonadecanyl Methanesulfonate | Succinimidyl 6-(4,4'-azipentanamido)hexanoate | Bis-(m-PEG8-amido)-hexanoic acid | (2S,4R)-1-[(2S)-2-acetamido-3-methylbutanoyl]-4-hydroxy-N-[(1S)-3-(methylamino)-3-oxo-1-phenylpropyl]pyrrolidine-2-carboxamide | XY-06-007 | (2S,4R)-4-hydroxy-N-[(1S)-3-(methylamino)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]-3-oxopropyl]-1-[(2R)-3-methyl-2-(3-methyl-1,2-oxazol-5-yl)butanoyl]pyrrolidine-2-carboxamide | Phosphonic acid,1,4-butanediylbis-, tetraethyl ester (9CI) | N-Succinimidyl 11-(maleimido)undecanoate | FF-10101 | N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide | THP-PEG4-alcohol
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