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Tos-PEG4-O-CH2COOH - CAS 2028284-73-1

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Tos-PEG4-O-CH2COOH is a PEG linker containing a tosyl group and a terminal carboxylic acid. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

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Molecular Formula
C17H26O9S
Molecular Weight
406.45

Tos-PEG4-O-CH2COOH

    • Specification
      • Purity
        ≥95%
        Solubility
        Soluble in DMSO
        Appearance
        Pale Yellow Oily Matter
        Storage
        Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
        Shipping
        Room temperature in continental US; may vary elsewhere.
        IUPAC Name
        2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]acetic acid
        Synonyms
        14-(Tosyloxy)-3,6,9,12-tetraoxatetradecanoic acid; Tos-PEG5-CH2CO2H; Tos-PEG5-CH2COOH; Tos-PEG4-CH2COOH; Acetic acid, 2-[2-[2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]ethoxy]ethoxy]-; 14-{[(4-Methylphenyl)sulfonyl]oxy}-3,6,9,12-tetraoxatetradecan-1-oic acid; 3,6,9,12-Tetraoxatetradecan-1-oic acid, 14-[[(4-methylphenyl)sulfonyl]oxy]-
    • Properties
      • Boiling Point
        567.7±50.0°C (Predicted)
        Density
        1.260±0.06 g/cm3 (Predicted)
        InChI Key
        MTBIBZOLTXFDIU-UHFFFAOYSA-N
        InChI
        InChI=1S/C17H26O9S/c1-15-2-4-16(5-3-15)27(20,21)26-13-12-24-9-8-22-6-7-23-10-11-25-14-17(18)19/h2-5H,6-14H2,1H3,(H,18,19)
        Canonical SMILES
        CC1=CC=C(S(=O)(OCCOCCOCCOCCOCC(O)=O)=O)C=C1
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L

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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