PROTAC Library - PROTAC® / BOC Sciences

Structure	Catalog	Product Name	CAS	E3 Ligase	Target	Inquiry
	BPL-202133	N-(2-(2-(4-((4-((2-(1H-Imidazol-1-yl)benzyl)amino)-8-isopropylpyrazolo[1,5-a][1,3,5]triazin-2-yl)oxy)piperidin-1-yl)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide		CRBN	CDK9	Inquiry
Molecular Weight: 833.91 Molecular Formula: C42H47N11O8 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202134	N-(2-(2-(2-(2-(4-((4-((2-(1H-Imidazol-1-yl)benzyl)amino)-8-isopropylpyrazolo[1,5-a][1,3,5]triazin-2-yl)oxy)piperidin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide		CRBN	CDK9	Inquiry
Molecular Weight: 922.01 Molecular Formula: C46H55N11O10 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202135	N-(2-(2-(4-((4-((2-(Dimethylamino)benzyl)amino)-8-isopropylpyrazolo[1,5-a][1,3,5]triazin-2-yl)oxy)piperidin-1-yl)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide		CRBN	CDK9	Inquiry
Molecular Weight: 810.91 Molecular Formula: C41H50N10O8 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202136	N-(2-(2-(2-(2-(4-((4-((2-(Dimethylamino)benzyl)amino)-8-isopropylpyrazolo[1,5-a][1,3,5]triazin-2-yl)oxy)piperidin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide		CRBN	CDK9	Inquiry
Molecular Weight: 899.02 Molecular Formula: C45H58N10O10 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202137	N-(2-(2-(4-((4-(Benzylamino)-8-isopropylpyrazolo[1,5-a][1,3,5]triazin-2-yl)oxy)piperidin-1-yl)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide		CRBN	CDK9	Inquiry
Molecular Weight: 767.84 Molecular Formula: C39H45N9O8 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202138	N-(2-(2-(2-(2-(4-((4-(Benzylamino)-8-isopropylpyrazolo[1,5-a][1,3,5]triazin-2-yl)oxy)piperidin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide		CRBN	CDK9	Inquiry
Molecular Weight: 855.95 Molecular Formula: C43H53N9O10 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202139	N-(6-(3-(((5-((6-Aminohexyl)amino)-3-isopropylpyrazolo[1,5-a]pyrimidin-7-yl)amino)methyl)phenyl)hexyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide	2411019-76-4	CRBN	CDK9	Inquiry
Molecular Weight: 793.97 Molecular Formula: C43H55N9O6 Density: 1.34±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202140	N-(6-(4-(((5-((6-Aminohexyl)amino)-3-isopropylpyrazolo[1,5-a]pyrimidin-7-yl)amino)methyl)phenyl)hexyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide	2411019-75-3	CRBN	CDK9	Inquiry
Molecular Weight: 793.97 Molecular Formula: C43H55N9O6 Density: 1.34±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202141	N-(6-(3-(Dimethylamino)-4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)hexyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide	2411019-84-4	CRBN	CDK9	Inquiry
Molecular Weight: 837.00 Molecular Formula: C44H56N10O7 Density: 1.38±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202142	N-(6-(4-(Dimethylamino)-3-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)hexyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide	2411019-85-5	CRBN	CDK9	Inquiry
Molecular Weight: 837.00 Molecular Formula: C44H56N10O7 Density: 1.38±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202143	N-(3-(Dimethylamino)-4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)-7-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)heptanamide	2411019-89-9	CRBN	CDK9	Inquiry
Molecular Weight: 880.02 Molecular Formula: C45H57N11O8 Density: 1.41±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202144	N-(4-(Dimethylamino)-3-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)-7-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)heptanamide	2411019-88-8	CRBN	CDK9	Inquiry
Molecular Weight: 880.02 Molecular Formula: C45H57N11O8 Density: 1.41±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202145	N-(3-(Dimethylamino)-4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)-7-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)heptanamide	2411019-90-2	CRBN	CDK9	Inquiry
Molecular Weight: 821.98 Molecular Formula: C43H55N11O6 Density: 1.39±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202146	4-((7-(2-(Dimethylamino)-3-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)heptyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione	2411019-82-2	CRBN	CDK9	Inquiry
Molecular Weight: 793.97 Molecular Formula: C43H55N9O6 Density: 1.35±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202147	4-((7-(3-(Dimethylamino)-4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)heptyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione	2411019-81-1	CRBN	CDK9	Inquiry
Molecular Weight: 793.97 Molecular Formula: C43H55N9O6 Density: 1.35±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202148	7-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)-N-(3-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)heptanamide	2411019-87-7	CRBN	CDK9	Inquiry
Molecular Weight: 836.95 Molecular Formula: C43H52N10O8 Density: 1.43±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202149	7-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)-N-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)heptanamide	2411019-86-6	CRBN	CDK9	Inquiry
Molecular Weight: 836.95 Molecular Formula: C43H52N10O8 Density: 1.43±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202150	7-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-N-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)heptanamide	2411019-91-3	CRBN	CDK9	Inquiry
Molecular Weight: 778.92 Molecular Formula: C41H50N10O6 Density: 1.42±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202151	7-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-N-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)heptanamide	2411019-95-7	CRBN	CDK9	Inquiry
Molecular Weight: 779.89 Molecular Formula: C41H49N9O7 Density: 1.42±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202152	6-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-N-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)hexanamide	2411019-93-5	CRBN	CDK9	Inquiry
Molecular Weight: 765.87 Molecular Formula: C40H47N9O7 Density: 1.43±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.