PROTAC Library - PROTAC® / BOC Sciences

Structure	Catalog	Product Name	CAS	E3 Ligase	Target	Inquiry
	BPL-202153	2-(2,6-Dioxopiperidin-3-yl)-4-((7-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)heptyl)oxy)isoindoline-1,3-dione	2411019-77-5	CRBN	CDK9	Inquiry
Molecular Weight: 750.89 Molecular Formula: C41H50N8O6 Density: 1.37±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202154	8-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-N-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)octanamide	2411019-97-9	CRBN	CDK9	Inquiry
Molecular Weight: 793.93 Molecular Formula: C42H51N9O7 Density: 1.40±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202155	9-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-N-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)nonanamide	2411019-99-1	CRBN	CDK9	Inquiry
Molecular Weight: 807.95 Molecular Formula: C43H53N9O7 Density: 1.39±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202156	2-(2-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)ethoxy)ethoxy)-N-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)acetamide	2411020-04-5	CRBN	CDK9	Inquiry
Molecular Weight: 797.87 Molecular Formula: C40H47N9O9 Density: 1.46±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202157	2-(2,6-Dioxopiperidin-3-yl)-4-(2-(2-(3-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)propoxy)ethoxy)ethoxy)isoindoline-1,3-dione	2411019-78-6	CRBN	CDK9	Inquiry
Molecular Weight: 782.89 Molecular Formula: C41H50N8O8 Density: 1.39±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202158	2-(2-(2-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)ethoxy)ethoxy)ethoxy)-N-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)acetamide	2411020-05-6	CRBN	CDK9	Inquiry
Molecular Weight: 841.92 Molecular Formula: C42H51N9O10 Density: 1.44±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202159	10-((2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)-N-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)decanamide	2411020-02-3	CRBN	CDK9	Inquiry
Molecular Weight: 807.98 Molecular Formula: C44H57N9O6 Density: 1.34±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202160	9-((2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)-N-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)nonanamide	2411020-00-1	CRBN	CDK9	Inquiry
Molecular Weight: 793.97 Molecular Formula: C43H55N9O6 Density: 1.36±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202161	8-((2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)-N-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)octanamide	2411019-98-0	CRBN	CDK9	Inquiry
Molecular Weight: 779.94 Molecular Formula: C42H53N9O6 Density: 1.37±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202162	7-((2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)-N-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)heptanamide	2411019-96-8	CRBN	CDK9	Inquiry
Molecular Weight: 765.92 Molecular Formula: C41H51N9O6 Density: 1.38±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202163	6-((2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)-N-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)hexanamide	2411019-94-6	CRBN	CDK9	Inquiry
Molecular Weight: 751.89 Molecular Formula: C40H49N9O6 Density: 1.40±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202164	7-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)-N-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)heptanamide	2411020-14-7	CRBN	CDK9	Inquiry
Molecular Weight: 749.92 Molecular Formula: C41H51N9O5 Density: 1.37±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202165	6-(4-(5-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)pentyl)piperazin-1-yl)-N-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)hexanamide	2411020-93-2	CRBN	CDK9	Inquiry
Molecular Weight: 890.15 Molecular Formula: C49H67N11O5 Density: 1.33±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202166	4-(4-(5-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)pentyl)piperazin-1-yl)-N-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)butanamide	2411020-87-4	CRBN	CDK9	Inquiry
Molecular Weight: 862.09 Molecular Formula: C47H63N11O5 Density: 1.36±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202167	6-(4-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)propyl)piperazin-1-yl)-N-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)hexanamide	2411020-91-0	CRBN	CDK9	Inquiry
Molecular Weight: 862.09 Molecular Formula: C47H63N11O5 Density: 1.36±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202168	4-(4-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)propyl)piperazin-1-yl)-N-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)butanamide	2411020-85-2	CRBN	CDK9	Inquiry
Molecular Weight: 834.04 Molecular Formula: C45H59N11O5 Density: 1.38±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202169	4-(5-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)pentyl)-N-(4-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)piperazine-1-carboxamide	2411020-69-2	CRBN	CDK9	Inquiry
Molecular Weight: 820.01 Molecular Formula: C44H57N11O5 Density: 1.40±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202170	4-(5-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)pentyl)-N-(4-(((5-(((S)-1-hydroxybutan-2-yl)amino)-3-isopropylpyrazolo[1,5-a]pyrimidin-7-yl)amino)methyl)phenyl)piperazine-1-carboxamide	2411021-01-5	CRBN	CDK9	Inquiry
Molecular Weight: 792.99 Molecular Formula: C43H56N10O5 Density: 1.37±0.1 g/cm3 Description: It is a potent and selective CDK9 degrader for targeting transcription regulation in triple-negative breast cancer.
	BPL-202171	N-[trans-4-(3-Chloro-4-cyanophenoxy)cyclohexyl]-4-[[3-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]amino]propyl]amino]benzamide	2757424-02-3	CRBN	AR	Inquiry
Molecular Weight: 683.17 Molecular Formula: C36H35ClN6O6 Boiling Point: 996.6±65.0°C at 760 Torr Density: 1.43±0.1 g/cm3 Description: It is an exceptionally potent and orally bioavailable PROTAC degrader of androgen receptor.
	BPL-202172	N-[trans-4-(3-Chloro-4-cyanophenoxy)cyclohexyl]-4-[[4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]amino]butyl]amino]benzamide	2757424-03-4	CRBN	AR	Inquiry
Molecular Weight: 697.19 Molecular Formula: C37H37ClN6O6 Boiling Point: 1001.1±65.0°C at 760 Torr Density: 1.42±0.1 g/cm3 Description: It is an exceptionally potent and orally bioavailable PROTAC degrader of androgen receptor.