PROTAC Library - PROTAC® / BOC Sciences

Structure	Catalog	Product Name	CAS	E3 Ligase	Target	Inquiry
	BPL-201473	4-(3,4-Dimethyl-7-oxo-2-(p-tolyl)-2,7-dihydro-6H-pyrazolo[3,4-d]pyridazin-6-yl)-N-(6-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)hexyl)butanamide	2428629-33-6	CRBN	PDEdelta	Inquiry
Molecular Weight: 694.79 Molecular Formula: C37H42N8O6 Density: 1.41±0.1 g/cm3 Description: It is a PDEδ degrader for the treatment of KRAS mutant colorectal cancer.
	BPL-201474	4-(3,4-Dimethyl-7-oxo-2-(p-tolyl)-2,7-dihydro-6H-pyrazolo[3,4-d]pyridazin-6-yl)-N-(7-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)heptyl)butanamide	2493974-08-4	CRBN	PDEdelta	Inquiry
Molecular Weight: 708.82 Molecular Formula: C38H44N8O6 Density: 1.39±0.1 g/cm3 Description: It is a PDEδ degrader for the treatment of KRAS mutant colorectal cancer.
	BPL-201475	4-(3,4-Dimethyl-7-oxo-2-(p-tolyl)-2,7-dihydro-6H-pyrazolo[3,4-d]pyridazin-6-yl)-N-(8-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)octyl)butanamide	2428629-35-8	CRBN	PDEdelta	Inquiry
Molecular Weight: 722.85 Molecular Formula: C39H46N8O6 Density: 1.37±0.1 g/cm3 Description: It is a PDEδ degrader for the treatment of KRAS mutant colorectal cancer.
	BPL-201476	4-(3,4-Dimethyl-7-oxo-2-(p-tolyl)-2,7-dihydro-6H-pyrazolo[3,4-d]pyridazin-6-yl)-N-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethyl)butanamide	2428629-36-9	CRBN	PDEdelta	Inquiry
Molecular Weight: 726.79 Molecular Formula: C37H42N8O8 Density: 1.43±0.1 g/cm3 Description: It is a PDEδ degrader for the treatment of KRAS mutant colorectal cancer.
	BPL-201477	4-(3,4-Dimethyl-7-oxo-2-(p-tolyl)-2,7-dihydro-6H-pyrazolo[3,4-d]pyridazin-6-yl)-N-(3-(2-(2-(3-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)propoxy)ethoxy)ethoxy)propyl)butanamide	2428629-38-1	CRBN	PDEdelta	Inquiry
Molecular Weight: 798.90 Molecular Formula: C41H50N8O9 Density: 1.38±0.1 g/cm3 Description: It is a PDEδ degrader for the treatment of KRAS mutant colorectal cancer.
	BPL-201478	4-(3,4-Dimethyl-7-oxo-2-(p-tolyl)-2,7-dihydro-6H-pyrazolo[3,4-d]pyridazin-6-yl)-N-(8-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)octyl)butanamide	2428629-40-5	CRBN	PDEdelta	Inquiry
Molecular Weight: 722.85 Molecular Formula: C39H46N8O6 Density: 1.37±0.1 g/cm3 Description: It is a PDEδ degrader for the treatment of KRAS mutant colorectal cancer.
	BPL-201479	P10lm	2512845-19-9	CRBN	BCR-ABL	Inquiry
Molecular Weight: 916.02 Molecular Formula: C49H49N13O6 Density: 1.45±0.1 g/cm3 Description: It is a PROTAC that degrades BCR-ABL.
	BPL-201480	P13lm	2512843-94-4	CRBN	BCR-ABL	Inquiry
Molecular Weight: 960.07 Molecular Formula: C51H53N13O7 Density: 1.43±0.1 g/cm3 Description: It is a PROTAC that degrades BCR-ABL.
	BPL-201481	P16lm	2635386-48-8	CRBN	BCR-ABL	Inquiry
Molecular Weight: 1004.12 Molecular Formula: C53H57N13O8 Density: 1.42±0.1 g/cm3 Description: It is a PROTAC that degrades BCR-ABL.
	BPL-201482	P19lm	2635386-49-9	CRBN	BCR-ABL	Inquiry
Molecular Weight: 1048.18 Molecular Formula: C55H61N13O9 Density: 1.40±0.1 g/cm3 Description: It is a PROTAC that degrades BCR-ABL.
	BPL-201483	P20lm	2635386-50-2	CRBN	BCR-ABL	Inquiry
Molecular Weight: 1092.23 Molecular Formula: C57H65N13O10 Density: 1.39±0.1 g/cm3 Description: It is a PROTAC that degrades BCR-ABL.
	BPL-201484	P10D	2512845-61-1	CRBN	BCR-ABL	Inquiry
Molecular Weight: 880.39 Molecular Formula: C41H42ClN13O6S Density: 1.59±0.1 g/cm3 Description: It is a PROTAC that degrades BCR-ABL.
	BPL-201485	P13D	2512843-46-6	CRBN	BCR-ABL	Inquiry
Molecular Weight: 924.45 Molecular Formula: C43H46ClN13O7S Density: 1.56±0.1 g/cm3 Description: It is a PROTAC that degrades BCR-ABL.
	BPL-201486	P16D	2512843-81-9	CRBN	BCR-ABL	Inquiry
Molecular Weight: 968.48 Molecular Formula: C45H50ClN13O8S Density: 1.53±0.1 g/cm3 Description: It is a PROTAC that degrades BCR-ABL.
	BPL-201487	P19D	2512844-41-4	CRBN	BCR-ABL	Inquiry
Molecular Weight: 1012.55 Molecular Formula: C47H54ClN13O9S Density: 1.51±0.1 g/cm3 Description: It is a PROTAC that degrades BCR-ABL.
	BPL-201488	P22D	2635386-51-3	CRBN	BCR-ABL	Inquiry
Molecular Weight: 1056.59 Molecular Formula: C49H58ClN13O10S Density: 1.49±0.1 g/cm3 Description: It is a PROTAC that degrades BCR-ABL.
	BPL-201489	P10As	2635386-52-4	CRBN	BCR-ABL	Inquiry
Molecular Weight: 885.29 Molecular Formula: C41H39ClF2N12O7 Density: 1.61±0.1 g/cm3 Description: It is a PROTAC that degrades BCR-ABL.
	BPL-201490	P13As	2635386-53-5	CRBN	BCR-ABL	Inquiry
Molecular Weight: 929.34 Molecular Formula: C43H43ClF2N12O8 Density: 1.58±0.1 g/cm3 Description: It is a PROTAC that degrades BCR-ABL.
	BPL-201491	P16As	2635386-54-6	CRBN	BCR-ABL	Inquiry
Molecular Weight: 973.38 Molecular Formula: C45H47ClF2N12O9 Density: 1.56±0.1 g/cm3 Description: It is a PROTAC that degrades BCR-ABL.
	BPL-201492	P19As	2635386-55-7	CRBN	BCR-ABL BCR-ABL T315I	Inquiry
Molecular Weight: 1017.45 Molecular Formula: C47H51ClF2N12O10 Density: 1.53±0.1 g/cm3 Description: It is a PROTAC that degrades BCR-ABL and drug-resistant mutant BCR-ABL T315I.