PROTAC Library

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E3 Ligase
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Structure Catalog Product Name CAS E3 Ligase Target Inquiry
d9A-2 BPL-201113 d9A-2 2690350-15-1

CRBN

SLC9A1
SLC9A2
SLC9A4
SLC9A7
SLC9B1

Inquiry

Molecular Weight: 867.98

Molecular Formula: C46H54FN7O9

Boiling Point: 1061.2±65.0°C at 760 Torr

Density: 1.315±0.06 g/cm3

Description: It is a PROTAC that targets the degradation of SLC transporters SLC9A1, SLC9A2, SLC9A4, SLC9A7, and SLC9B1.

d9A-3 BPL-201114 d9A-3 2640254-11-9

CRBN

SLC9A1

Inquiry

Molecular Weight: 910.01

Molecular Formula: C48H56FN7O10

Boiling Point: 1132.1±65.0°C at 760 Torr

Density: 1.305±0.06 g/cm3

Description: It is a PROTAC that targets the degradation of SLC transporter SLC9A1.

d9A-4 BPL-201115 d9A-4 2640254-12-0

CRBN

SLC9A1

Inquiry

Molecular Weight: 837.91

Molecular Formula: C44H48FN7O9

Boiling Point: 1100.5±65.0°C at 760 Torr

Density: 1.341±0.06 g/cm3

Description: It is a PROTAC that targets the degradation of SLC transporter SLC9A1.

d9A-5 BPL-201116 d9A-5 2640254-10-8

CRBN

SLC9A1

Inquiry

Molecular Weight: 805.91

Molecular Formula: C44H48FN7O7

Boiling Point: 1079.9±65.0°C at 760 Torr

Density: 1.316±0.06 g/cm3

Description: It is a PROTAC that targets the degradation of SLC transporter SLC9A1.

TL13-117 BPL-201117 TL13-117

CRBN

BLK
CDK5
FER
FLT3
GAK
IRAK1
LCK
MAP4K2
p38alpha
RIPK1
Src

Inquiry

Molecular Weight: 1004.14

Molecular Formula: C50H57N11O10S

Description: It is a selective degrader for BLK, CDK5, FER, FLT3, GAK, IRAK1, LCK, MAP4K2, p38alpha, RIPK1, and Src, and has the potential to improve disease treatment.

TL13-148 BPL-201118 TL13-148

CRBN

FLT3

Inquiry

Molecular Weight: 891.96

Molecular Formula: C44H45N9O10S

Description: It is a selective FLT3 degrader, and has the potential to improve disease treatment.

TL13-149 BPL-201119 TL13-149 2801715-14-8

CRBN

FLT3

Inquiry

Molecular Weight: 936.02

Molecular Formula: C46H49N9O11S

Density: 1.48±0.1 g/cm3

Description: It is a selective FLT3 degrader, and has the potential to improve disease treatment.

JB-4-048 BPL-201120 JB-4-048

CRBN

FLT3

Inquiry

Molecular Weight: 1044.16

Molecular Formula: C52H57N11O11S

Description: It is a selective FLT3 degrader, and has the potential to improve disease treatment.

JB-4-049 BPL-201121 JB-4-049 2769852-42-6

CRBN

FLT3

Inquiry

Molecular Weight: 1100.27

Molecular Formula: C56H65N11O11S

Density: 1.43±0.1 g/cm3

Description: It is a selective FLT3 degrader, and has the potential to improve disease treatment.

JB-4-050 BPL-201122 JB-4-050

CRBN

FLT3

Inquiry

Molecular Weight: 1176.32

Molecular Formula: C58H69N11O14S

Description: It is a selective FLT3 degrader, and has the potential to improve disease treatment.

JB-4-066 BPL-201123 JB-4-066

CRBN

FLT3

Inquiry

Molecular Weight: 1002.12

Molecular Formula: C50H55N11O10S

Description: It is a selective FLT3 degrader, and has the potential to improve disease treatment.

JB-4-072 BPL-201124 JB-4-072

CRBN

FLT3

Inquiry

Molecular Weight: 1058.23

Molecular Formula: C54H63N11O10S

Description: It is a selective FLT3 degrader, and has the potential to improve disease treatment.

JB-4-073 BPL-201125 JB-4-073

CRBN

FLT3

Inquiry

Molecular Weight: 1134.28

Molecular Formula: C56H67N11O13S

Description: It is a selective FLT3 degrader, and has the potential to improve disease treatment.

CJH-005-067 BPL-201126 CJH-005-067 2102694-54-0

CRBN

BTK

Inquiry

Molecular Weight: 903.82

Molecular Formula: C44H48Cl2N8O9

Boiling Point: 1011.7±65.0°C at 760 Torr

Density: 1.45±0.1 g/cm3

Description: It is a selective BTK degrader, and has the potential to improve disease treatment.

DD-04-015 BPL-201127 DD-04-015

CRBN

BTK

Inquiry

Molecular Weight: 1037.12

Molecular Formula: C55H57FN10O10

Description: It is a selective BTK degrader, and has the potential to improve disease treatment.

ZNL-02-012 BPL-201128 ZNL-02-012 2414418-43-0

CRBN

Wee1

Inquiry

Molecular Weight: 959.08

Molecular Formula: C49H58N12O9

Density: 1.366±0.06 g/cm3

Description: It is a selective Wee1 degrader.

ZNL-02-047 BPL-201129 ZNL-02-047 2414418-48-5

CRBN

Wee1

Inquiry

Molecular Weight: 918.03

Molecular Formula: C47H55N11O9

Density: 1.372±0.06 g/cm3

Description: It is a selective Wee1 degrader.

ZNL-02-040 BPL-201130 ZNL-02-040 2414418-47-4

CRBN

Wee1

Inquiry

Molecular Weight: 841.97

Molecular Formula: C45H51N11O6

Density: 1.364±0.06 g/cm3

Description: It is a selective Wee1 degrader.

N1-(2-(1-(3-Bromo-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxamido)ethyl)-N5-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glutaramide BPL-201131 N1-(2-(1-(3-Bromo-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxamido)ethyl)-N5-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glutaramide 2447066-15-9

CRBN

PD-L1

Inquiry

Molecular Weight: 905.85

Molecular Formula: C47H49BrN6O8

Boiling Point: 1116.1±65.0°C at 760 Torr

Density: 1.401±0.06 g/cm3

Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.

5-(4-(1-(3-Bromo-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carbonyl)piperazin-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-5-oxopentanamide BPL-201132 5-(4-(1-(3-Bromo-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carbonyl)piperazin-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-5-oxopentanamide 2447066-16-0

CRBN

PD-L1

Inquiry

Molecular Weight: 931.89

Molecular Formula: C49H51BrN6O8

Boiling Point: 1088.3±65.0°C at 760 Torr

Density: 1.415±0.06 g/cm3

Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.

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