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E3 Ligase
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Structure Catalog Product Name CAS E3 Ligase Target Inquiry
iRucaparib-TP1 BPL-201173 iRucaparib-TP1 2472644-69-0

CRBN

PARP1

Inquiry

Molecular Weight: 789.87

Molecular Formula: C42H44FN9O6

Density: 1.47±0.1 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

iRucaparib-TP2 BPL-201174 iRucaparib-TP2 2472644-70-3

CRBN

PARP1

Inquiry

Molecular Weight: 833.92

Molecular Formula: C44H48FN9O7

Density: 1.45±0.1 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

iRucaparib-TP3 BPL-201175 iRucaparib-TP3 2410557-01-4

CRBN

PARP1

Inquiry

Molecular Weight: 877.98

Molecular Formula: C46H52FN9O8

Density: 1.43±0.1 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

iRucaparib-TP4 BPL-201176 iRucaparib-TP4 2472644-71-4

CRBN

PARP1

Inquiry

Molecular Weight: 922.03

Molecular Formula: C48H56FN9O9

Density: 1.42±0.1 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

iRucaparib-TP5 BPL-201177 iRucaparib-TP5 2472644-72-5

CRBN

PARP1

Inquiry

Molecular Weight: 966.08

Molecular Formula: C50H60FN9O10

Density: 1.40±0.1 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

iRucaparib-AMP3-1 BPL-201178 iRucaparib-AMP3-1 2472644-75-8

CRBN

PARP1

Inquiry

Molecular Weight: 853.95

Molecular Formula: C45H52FN7O9

Boiling Point: 1115.9±65.0°C at 760 Torr

Density: 1.341±0.06 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

iRucaparib-AMP3-2 BPL-201179 iRucaparib-AMP3-2 2472644-76-9

CRBN

PARP1

Inquiry

Molecular Weight: 867.98

Molecular Formula: C46H54FN7O9

Boiling Point: 1118.1±65.0°C at 760 Torr

Density: 1.329±0.06 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

iRucaparib-ITP3 BPL-201180 iRucaparib-ITP3

CRBN

PARP1

Inquiry

Molecular Weight: 892.00

Molecular Formula: C47H54FN9O8

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

iRucaparib-ITP4 BPL-201181 iRucaparib-ITP4

CRBN

PARP1

Inquiry

Molecular Weight: 936.06

Molecular Formula: C49H58FN9O9

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

iRucaparib-AP4 BPL-201182 iRucaparib-AP4

CRBN

PARP1

Inquiry

Molecular Weight: 798.87

Molecular Formula: C42H47FN6O9

Boiling Point: 1030.6±65.0°C at 760 Torr

Density: 1.4±0.1 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

iRucaparib-AP5 BPL-201183 iRucaparib-AP5 2472644-77-0

CRBN

PARP1
PARP3

Inquiry

Molecular Weight: 842.92

Molecular Formula: C44H51FN6O10

Boiling Point: 1043.7±65.0°C at 760 Torr

Density: 1.344±0.06 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 and PARP3 with high efficiency and specificity.

iRucaparib-AP6 BPL-201184 iRucaparib-AP6 2410557-00-3

CRBN

PARP1
PARP3

Inquiry

Molecular Weight: 886.98

Molecular Formula: C46H55FN6O11

Boiling Point: 1057.6±65.0°C at 760 Torr

Density: 1.331±0.06 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 and PARP3 with high efficiency and specificity.

iRucaparib-AP7 BPL-201185 iRucaparib-AP7 2472644-78-1

CRBN

PARP1

Inquiry

Molecular Weight: 931.03

Molecular Formula: C48H59FN6O12

Boiling Point: 1072.0±65.0°C at 760 Torr

Density: 1.319±0.06 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

vRucaparib-TP3 BPL-201186 vRucaparib-TP3 2472644-73-6

VHL

PARP1

Inquiry

Molecular Weight: 1063.31

Molecular Formula: C56H71FN10O8S

Density: 1.34±0.1 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

vRucaparib-TP4 BPL-201187 vRucaparib-TP4 2410557-03-6

VHL

PARP1

Inquiry

Molecular Weight: 1107.36

Molecular Formula: C58H75FN10O9S

Density: 1.33±0.1 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

iVeliparib-AP4 BPL-201188 iVeliparib-AP4

CRBN

PARP1
PARP2

Inquiry

Molecular Weight: 719.80

Molecular Formula: C36H45N7O9

Boiling Point: 982.2±65.0°C at 760 Torr

Density: 1.4±0.1 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 and PARP2 with high efficiency and specificity.

iVeliparib-AP5 BPL-201189 iVeliparib-AP5 2472645-26-2

CRBN

PARP1
PARP2

Inquiry

Molecular Weight: 763.85

Molecular Formula: C38H49N7O10

Boiling Point: 995.5±65.0°C at 760 Torr

Density: 1.346±0.06 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 and PARP2 with high efficiency and specificity.

iVeliparib-AP6 BPL-201190 iVeliparib-AP6 2472645-27-3

CRBN

PARP2
PARP1

Inquiry

Molecular Weight: 807.89

Molecular Formula: C40H53N7O11

Boiling Point: 1009.7±65.0°C at 760 Torr

Density: 1.331±0.06 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 and PARP2 with high efficiency and specificity.

iVeliparib-AP7 BPL-201191 iVeliparib-AP7 2472645-28-4

CRBN

PARP1
PARP2

Inquiry

Molecular Weight: 851.96

Molecular Formula: C42H57N7O12

Boiling Point: 1024.5±65.0°C at 760 Torr

Density: 1.318±0.06 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 and PARP2 with high efficiency and specificity.

iNiraparib-AP4 BPL-201192 iNiraparib-AP4

CRBN

PARP1

Inquiry

Molecular Weight: 795.89

Molecular Formula: C42H49N7O9

Boiling Point: 921.1±65.0°C at 760 Torr

Density: 1.4±0.1 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

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