PROTAC Library - PROTAC® / BOC Sciences

Structure	Catalog	Product Name	CAS	E3 Ligase	Target	Inquiry
	BPL-201133	1-(3-Bromo-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)-N-(4-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)piperidine-2-carboxamide	2447066-17-1	CRBN	PD-L1	Inquiry
Molecular Weight: 820.79 Molecular Formula: C44H46BrN5O6 Boiling Point: 987.3±65.0°C at 760 Torr Density: 1.381±0.06 g/cm3 Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.
	BPL-201134	N1-(2-(1-(5-Chloro-2-((3-cyanobenzyl)oxy)-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxamido)ethyl)-N5-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glutaramide	2447066-18-2	CRBN	PD-L1	Inquiry
Molecular Weight: 992.53 Molecular Formula: C55H54ClN7O9 Boiling Point: 1193.9±65.0°C at 760 Torr Density: 1.40±0.1 g/cm3 Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.
	BPL-201135	N1-(4-(1-(5-Chloro-2-((3-cyanobenzyl)oxy)-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxamido)butyl)-N5-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glutaramide	2447066-19-3	CRBN	PD-L1	Inquiry
Molecular Weight: 1020.58 Molecular Formula: C57H58ClN7O9 Boiling Point: 1204.2±65.0°C at 760 Torr Density: 1.38±0.1 g/cm3 Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.
	BPL-201136	N1-(3-(1-(5-Chloro-2-((3-cyanobenzyl)oxy)-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxamido)propyl)-N5-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glutaramide		CRBN	PD-L1	Inquiry
Molecular Weight: 1006.56 Molecular Formula: C56H56ClN7O9 Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.
	BPL-201137	N1-(5-(1-(5-Chloro-2-((3-cyanobenzyl)oxy)-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxamido)pentyl)-N5-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glutaramide	2447066-21-7	CRBN	PD-L1	Inquiry
Molecular Weight: 1034.61 Molecular Formula: C58H60ClN7O9 Boiling Point: 1207.0±65.0°C at 760 Torr Density: 1.37±0.1 g/cm3 Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.
	BPL-201138	N1-(2-(1-(5-Chloro-2-((3-cyanobenzyl)oxy)-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxamido)ethyl)-N5-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)glutaramide	2447066-22-8	CRBN	PD-L1	Inquiry
Molecular Weight: 992.53 Molecular Formula: C55H54ClN7O9 Boiling Point: 1196.7±65.0°C at 760 Torr Density: 1.40±0.1 g/cm3 Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.
	BPL-201139	5-(4-(1-(5-Chloro-2-((3-cyanobenzyl)oxy)-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carbonyl)piperazin-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-5-oxopentanamide	2447066-23-9	CRBN	PD-L1	Inquiry
Molecular Weight: 1018.57 Molecular Formula: C57H56ClN7O9 Density: 1.42±0.1 g/cm3 Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.
	BPL-201140	4-(4-(1-(5-Chloro-2-((3-cyanobenzyl)oxy)-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carbonyl)piperazin-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-4-oxobutanamide	2447066-24-0	CRBN	PD-L1	Inquiry
Molecular Weight: 1004.54 Molecular Formula: C56H54ClN7O9 Density: 1.43±0.1 g/cm3 Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.
	BPL-201141	1-(5-Chloro-2-((3-cyanobenzyl)oxy)-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)-N-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)piperidine-2-carboxamide	2447066-25-1	CRBN	PD-L1	Inquiry
Molecular Weight: 879.41 Molecular Formula: C50H47ClN6O7 Boiling Point: 1061.9±65.0°C at 760 Torr Density: 1.40±0.1 g/cm3 Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.
	BPL-201142	1-(5-Chloro-2-((3-cyanobenzyl)oxy)-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)-N-(3-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)propyl)piperidine-2-carboxamide	2447066-26-2	CRBN	PD-L1	Inquiry
Molecular Weight: 893.44 Molecular Formula: C51H49ClN6O7 Boiling Point: 1068.0±65.0°C at 760 Torr Density: 1.39±0.1 g/cm3 Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.
	BPL-201143	1-(5-Chloro-2-((3-cyanobenzyl)oxy)-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)-N-(4-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)piperidine-2-carboxamide	2447066-27-3	CRBN	PD-L1	Inquiry
Molecular Weight: 907.47 Molecular Formula: C52H51ClN6O7 Boiling Point: 1074.3±65.0°C at 760 Torr Density: 1.38±0.1 g/cm3 Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.
	BPL-201144	1-(5-Chloro-2-((3-cyanobenzyl)oxy)-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)-N-(5-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)pentyl)piperidine-2-carboxamide	2447066-29-5	CRBN	PD-L1	Inquiry
Molecular Weight: 921.49 Molecular Formula: C53H53ClN6O7 Boiling Point: 1078.3±65.0°C at 760 Torr Density: 1.37±0.1 g/cm3 Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.
	BPL-201145	1-(5-Chloro-2-((3-cyanobenzyl)oxy)-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)-N-(6-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)hexyl)piperidine-2-carboxamide	2447066-30-8	CRBN	PD-L1	Inquiry
Molecular Weight: 935.52 Molecular Formula: C54H55ClN6O7 Boiling Point: 1082.4±65.0°C at 760 Torr Density: 1.35±0.1 g/cm3 Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.
	BPL-201146	N1-(2-(1-(5-Chloro-2-((3-cyanobenzyl)oxy)-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxamido)ethyl)-N4-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)succinamide	2447066-31-9	CRBN	PD-L1	Inquiry
Molecular Weight: 978.50 Molecular Formula: C54H52ClN7O9 Boiling Point: 1188.3±65.0°C at 760 Torr Density: 1.42±0.1 g/cm3 Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.
	BPL-201147	1-(5-Chloro-2-((3-cyanobenzyl)oxy)-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)-N-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-2-oxoethoxy)acetamido)ethyl)piperidine-2-carboxamide	2447066-32-0	CRBN	PD-L1	Inquiry
Molecular Weight: 994.50 Molecular Formula: C54H52ClN7O10 Boiling Point: 1190.4±65.0°C at 760 Torr Density: 1.43±0.1 g/cm3 Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.
	BPL-201148	N1-(2-(1-(5-Chloro-2-((3-cyanobenzyl)oxy)-4-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)benzyl)piperidine-2-carboxamido)ethyl)-N5-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glutaramide	2447066-33-1	CRBN	PD-L1	Inquiry
Molecular Weight: 1050.57 Molecular Formula: C57H56ClN7O11 Density: 1.44±0.1 g/cm3 Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.
	BPL-201149	N1-(2-(1-(5-Chloro-2-((3-cyanobenzyl)oxy)-4-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)benzyl)piperidine-2-carboxamido)ethyl)-N5-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)glutaramide	2447066-34-2	CRBN	PD-L1	Inquiry
Molecular Weight: 1050.57 Molecular Formula: C57H56ClN7O11 Density: 1.44±0.1 g/cm3 Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.
	BPL-201150	1-(5-Chloro-2-((3-cyanobenzyl)oxy)-4-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)benzyl)-N-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-2-oxoethoxy)acetamido)ethyl)piperidine-2-carboxamide	2447066-35-3	CRBN	PD-L1	Inquiry
Molecular Weight: 1052.54 Molecular Formula: C56H54ClN7O12 Density: 1.46±0.1 g/cm3 Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.
	BPL-201151	N1-(2-(1-(5-Chloro-2-((3-cyanobenzyl)oxy)-4-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)benzyl)piperidine-2-carboxamido)ethyl)-N4-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)succinamide	2447066-36-4	CRBN	PD-L1	Inquiry
Molecular Weight: 1036.54 Molecular Formula: C56H54ClN7O11 Density: 1.45±0.1 g/cm3 Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.
	BPL-201152	4-(4-(1-(5-Chloro-2-((3-cyanobenzyl)oxy)-4-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)benzyl)piperidine-2-carbonyl)piperazin-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-4-oxobutanamide	2447066-38-6	CRBN	PD-L1	Inquiry
Molecular Weight: 1062.58 Molecular Formula: C58H56ClN7O11 Density: 1.46±0.1 g/cm3 Description: It is a resorcinol diphenyl ether-based PROTAC-like molecule as a dual inhibitor and degrader of PD-L1.