PROTAC Library

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E3 Ligase
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Structure Catalog Product Name CAS E3 Ligase Target Inquiry
iNiraparib-AP5 BPL-201193 iNiraparib-AP5 2472645-29-5

CRBN

PARP1

Inquiry

Molecular Weight: 839.95

Molecular Formula: C44H53N7O10

Boiling Point: 939.7±65.0°C at 760 Torr

Density: 1.39±0.1 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

iNiraparib-AP6 BPL-201194 iNiraparib-AP6 2472645-30-8

CRBN

PARP1

Inquiry

Molecular Weight: 883.99

Molecular Formula: C46H57N7O11

Boiling Point: 958.3±65.0°C at 760 Torr

Density: 1.38±0.1 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

iNiraparib-AP7 BPL-201195 iNiraparib-AP7 2472645-31-9

CRBN

PARP1

Inquiry

Molecular Weight: 928.05

Molecular Formula: C48H61N7O12

Boiling Point: 976.9±65.0°C at 760 Torr

Density: 1.36±0.1 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

iOlaparib-AP3 BPL-201196 iOlaparib-AP3

CRBN

PARP1

Inquiry

Molecular Weight: 811.82

Molecular Formula: C41H42FN7O10

Density: 1.5±0.1 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

iOlaparib-AP4 BPL-201197 iOlaparib-AP4

CRBN

PARP1

Inquiry

Molecular Weight: 855.88

Molecular Formula: C43H46FN7O11

Density: 1.5±0.1 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

iOlaparib-AP5 BPL-201198 iOlaparib-AP5

CRBN

PARP1

Inquiry

Molecular Weight: 899.93

Molecular Formula: C45H50FN7O12

Density: 1.4±0.1 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

iOlaparib-AP6 BPL-201199 iOlaparib-AP6

CRBN

PARP1

Inquiry

Molecular Weight: 943.98

Molecular Formula: C47H54FN7O13

Density: 1.4±0.1 g/cm3

Description: It is a small molecule PARP degrader that can degrade PARP1 with high efficiency and specificity.

DFCI-4107 BPL-201200 DFCI-4107 2170695-15-3

VHL

TRIM24

Inquiry

Molecular Weight: 1228.48

Molecular Formula: C61H81N9O14S2

Density: 1.280±0.06 g/cm3

Description: It is a functional TRIM24 degrader via conjugation of an ineffectual bromodomain and a VHL ligand.

dTAG-48 BPL-201201 dTAG-48 1957235-15-2

CRBN

FKBP12 F36V

Inquiry

Molecular Weight: 1210.34

Molecular Formula: C63H79N5O19

Boiling Point: 1242.1±65.0°C at 760 Torr

Density: 1.265±0.06 g/cm3

Description: It is a degrader of FKBP12F36V.

dTAG-51 BPL-201202 dTAG-51 1957235-39-0

CRBN

FKBP12 F36V

Inquiry

Molecular Weight: 1076.25

Molecular Formula: C59H73N5O14

Boiling Point: 1155.3±65.0°C at 760 Torr

Density: 1.250±0.06 g/cm3

Description: It is a degrader of FKBP12F36V.

YZ166 BPL-201203 YZ166

CRBN

HDAC6

Inquiry

Molecular Weight: 587.63

Molecular Formula: C31H33N5O7

Description: It is an HDAC6 degrader with cellular protein degradation activity.

YZ167 BPL-201204 YZ167

CRBN

HDAC6

Inquiry

Molecular Weight: 615.69

Molecular Formula: C33H37N5O7

Description: It is an HDAC6 degrader with cellular protein degradation activity.

YZ168 BPL-201205 YZ168

CRBN

HDAC6

Inquiry

Molecular Weight: 533.59

Molecular Formula: C28H31N5O6

Description: It is an HDAC6 degrader with cellular protein degradation activity.

WH629 BPL-201206 WH629

CRBN

HDAC6

Inquiry

Molecular Weight: 813.92

Molecular Formula: C44H47N9O7

Description: It is an HDAC6 degrader with cellular protein degradation activity.

WH624 BPL-201207 WH624

CRBN

HDAC6

Inquiry

Molecular Weight: 827.94

Molecular Formula: C45H49N9O7

Description: It is an HDAC6 degrader with cellular protein degradation activity.

WH623 BPL-201208 WH623

CRBN

HDAC6

Inquiry

Molecular Weight: 841.97

Molecular Formula: C46H51N9O7

Description: It is an HDAC6 degrader with cellular protein degradation activity.

YZ273 BPL-201209 YZ273

CRBN

HDAC6

Inquiry

Molecular Weight: 856.00

Molecular Formula: C47H53N9O7

Description: It is an HDAC6 degrader with cellular protein degradation activity.

WH641 BPL-201210 WH641

CRBN

HDAC6

Inquiry

Molecular Weight: 870.02

Molecular Formula: C48H55N9O7

Description: It is an HDAC6 degrader with cellular protein degradation activity.

YZ268 BPL-201211 YZ268

CRBN

HDAC6

Inquiry

Molecular Weight: 884.05

Molecular Formula: C49H57N9O7

Description: It is an HDAC6 degrader with cellular protein degradation activity.

BJG-02-098 BPL-201212 BJG-02-098

CRBN

Alpha-tubulin
Beta-tubulin

Inquiry

Molecular Weight: 1193.49

Molecular Formula: C62H96N8O15

Description: It is a tubulin-targeted small molecule degrader.

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