Structure	Catalog	Product Name	CAS	E3 Ligase	Target	Inquiry
	BPL-201093	TMX-1128	2488892-02-8	CRBN	CDK2	Inquiry
Molecular Weight: 932.78 Molecular Formula: C38H43BrFN9O11S Density: 1.62±0.1 g/cm3 Description: It is a heterobifunctional CDK2 degrader.
	BPL-201094	TMX-1111		CRBN	CDK2	Inquiry
Molecular Weight: 1020.89 Molecular Formula: C42H51BrFN9O13S Description: It is a heterobifunctional CDK2 degrader.
	BPL-201095	TMX-1146		CRBN	CDK2	Inquiry
Molecular Weight: 1197.09 Molecular Formula: C50H67BrFN9O17S Description: It is a heterobifunctional CDK2 degrader.
	BPL-201096	TMX-1169	2488892-05-1	CRBN	CDK2	Inquiry
Molecular Weight: 886.76 Molecular Formula: C37H41BrFN9O9S Density: 1.62±0.1 g/cm3 Description: It is a heterobifunctional CDK2 degrader.
	BPL-201097	TMX-1162		CRBN	CDK2	Inquiry
Molecular Weight: 914.81 Molecular Formula: C39H45BrFN9O9S Description: It is a heterobifunctional CDK2 degrader.
	BPL-201098	TMX-1160	2488752-66-3	CRBN	AURKA CDK1 CDK12 CDK16 CDK17 CDK2 CDK4 CDK5 CDK6 CDK7 CDK9 MAPK10 MAPK8 MAPK9 RPS6KA1	Inquiry
Molecular Weight: 928.84 Molecular Formula: C40H47BrFN9O9S Density: 1.56±0.1 g/cm3 Description: It is a heterobifunctional degrader of AURKA, CDK1, CDK12, CDK16, CDK17, CDK2, CDK4, CDK5, CDK6, CDK7, CDK9, MAPK10, MAPK8, MAPK9, and RPS6KA1.
	BPL-201099	TMX-2138	2488892-07-3	CRBN	AAK1 AURKA AURKB CDK1 CDK12 CDK16 CDK17 CDK2 CDK5 CDK7 CDK9 CLK1 FER GSK3A GSK-3beta IRAK3 MAP3K11 MAPK8 MAPK9 NUAK1 PRKAA1 PRKAA2 PTK2B RPS6KA1 RPS6KA3 STK33 STK38 TTK	Inquiry
Molecular Weight: 956.81 Molecular Formula: C40H43BrFN9O11S Density: 1.548±0.06 g/cm3 Description: It is a heterobifunctional degrader of AAK1, AURKA, AURKB, CDK1, CDK12, CDK16, CDK17, CDK2, CDK5, CDK7, CDK9, CLK1, FER, GSK3A, GSK-3beta, IRAK3, MAP3K11, MAPK8, MAPK9, NUAK1, PRKAA1, PRKAA2, PTK2B, RPS6KA1, RPS6KA3, STK33, STK38, and TTK.
	BPL-201100	TMX-2172	2488892-09-5	CRBN	AURKA AURKB CDK1 CDK2 CDK5 FAK MAPK8 MAPK9 RPS6KA1 RPS6KA3 STK33 TTK	Inquiry
Molecular Weight: 970.83 Molecular Formula: C41H45BrFN9O11S Density: 1.531±0.06 g/cm3 Description: TMX-2172 is a heterobifunctional CDK2 degrader with degradation selectivity for CDK2 and CDK5 over not only CDK1, but transcriptional CDKs (CDK7 and CDK9) and cell cycle CDKs (CDK4 and CDK6) as well.
	BPL-201101	TMX-2174	2488892-08-4	CRBN	AAK1 AURKA AURKB CDK1 CDK12 CDK16 CDK17 CDK2 CDK5 CDK7 CDK9 CLK1 FAK FER GSK3A GSK-3beta IRAK3 MAP3K11 MAPK8 MAPK9 NEK1 NEK3 NEK4 NEK9 NUAK1 PRKAA1 PRKAA2 PTK2B RPS6KA1 RPS6KA3 RPS6KA4 STK33 STK35 STK38 TBK1 TEC TTK Wee1	Inquiry
Molecular Weight: 970.83 Molecular Formula: C41H45BrFN9O11S Density: 1.531±0.06 g/cm3 Description: It is a heterobifunctional degrader of AAK1, AURKA, AURKB, CDK1, CDK12, CDK16, CDK17, CDK2, CDK5, CDK7, CDK9, CLK1, FAK, FER, GSK3A, GSK-3beta, IRAK3, MAP3K11, MAPK8, MAPK9, NEK1, NEK3, NEK4, NEK9, NUAK1, PRKAA1, PRKAA2, PTK2B, RPS6KA1, RPS6KA3, RPS6KA4, STK33, STK35, STK38, TBK1, TEC, TTK, and Wee1.
	BPL-201102	4-(2-(2,4-Difluorophenoxy)-5-(ethylsulfonamido)phenyl)-N-((1-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)amino)-2-oxoethoxy)ethyl)-1H-1,2,3-triazol-4-yl)methyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide	2410947-56-5	CRBN	BRD4	Inquiry
Molecular Weight: 926.92 Molecular Formula: C43H40F2N10O10S Density: 1.59±0.1 g/cm3 Description: It is a BRD4 degrader that degrades BRD4 protein and inhibits tumor growth.
	BPL-201103	4-(2-(2,4-Difluorophenoxy)-5-(ethylsulfonamido)phenyl)-N-((1-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)amino)-2-oxoethoxy)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)methyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide	2410947-57-6	CRBN	BRD4	Inquiry
Molecular Weight: 970.97 Molecular Formula: C45H44F2N10O11S Density: 1.57±0.1 g/cm3 Description: It is a BRD4 degrader that degrades BRD4 protein and inhibits tumor growth.
	BPL-201104	4-(2-(2,4-Difluorophenoxy)-5-(ethylsulfonamido)phenyl)-N-((1-(2-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)amino)-2-oxoethoxy)ethoxy)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)methyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide	2410947-58-7	CRBN	BRD4	Inquiry
Molecular Weight: 1015.02 Molecular Formula: C47H48F2N10O12S Density: 1.54±0.1 g/cm3 Description: It is a BRD4 degrader that degrades BRD4 protein and inhibits tumor growth.
	BPL-201105	4-(2-(2,4-Difluorophenoxy)-5-(ethylsulfonamido)phenyl)-N-((1-(14-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)amino)-14-oxo-3,6,9,12-tetraoxatetradecyl)-1H-1,2,3-triazol-4-yl)methyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide	2410947-59-8	CRBN	BRD4	Inquiry
Molecular Weight: 1059.07 Molecular Formula: C49H52F2N10O13S Density: 1.52±0.1 g/cm3 Description: It is a BRD4 degrader that degrades BRD4 protein and inhibits tumor growth.
	BPL-201106	2-(2-Acrylamido-5-methoxy-4-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)-5-methyl-8,11-dioxa-2,5-diazatridecan-13-amide	2488653-35-4	CRBN	EGFR	Inquiry
Molecular Weight: 872.98 Molecular Formula: C46H52N10O8 Density: 1.35±0.1 g/cm3 Description: It is an EGFR degrader based on osimertinib and lenalidomide.
	BPL-201107	2-(2-Acrylamido-5-methoxy-4-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)-5-methyl-8,11,14-trioxa-2,5-diazahexadecan-16-amide	2488653-36-5	CRBN	EGFR	Inquiry
Molecular Weight: 917.04 Molecular Formula: C48H56N10O9 Density: 1.34±0.1 g/cm3 Description: It is an EGFR degrader based on osimertinib and lenalidomide.
	BPL-201108	2-(2-Acrylamido-5-methoxy-4-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)-5-methyl-8,11,14,17-tetraoxa-2,5-diazanonadecan-19-amide	2488653-37-6	CRBN	EGFR	Inquiry
Molecular Weight: 961.09 Molecular Formula: C50H60N10O10 Density: 1.33±0.1 g/cm3 Description: It is an EGFR degrader based on osimertinib and lenalidomide.
	BPL-201109	DD-03-007	2227215-24-7	CRBN	BTK BTK C481S	Inquiry
Molecular Weight: 1023.16 Molecular Formula: C55H62N10O10 Density: 1.36±0.1 g/cm3 Description: It is a BTK degrader that can potently inhibit the signal and proliferation of cancer cells and effectively degrade C481S-BTK.
	BPL-201110	DD-03-171	2366132-45-6	CRBN	BTK BTK C481S	Inquiry
Molecular Weight: 991.16 Molecular Formula: C55H62N10O8 Density: 1.34±0.1 g/cm3 Description: DD-03-171 shows an enhanced anti-proliferative effect against mantle cell lymphoma (MCL) cells in vitro by degrading BTK, IKFZ1, and IKFZ3, and is effective against patient-derived xenografts in vivo.
	BPL-201111	DD-04-118	2516246-00-5	CRBN	BTK	Inquiry
Molecular Weight: 992.15 Molecular Formula: C55H61N9O9 Density: 1.34±0.1 g/cm3 Description: It is a BTK degrader that can potently inhibit the signal and proliferation of cancer cells.
	BPL-201112	d9A-1		CRBN	SLC9A1	Inquiry
Molecular Weight: 881.96 Molecular Formula: C46H52FN7O10 Description: It is a PROTAC that targets the degradation of SLC transporter SLC9A1.

PROTAC Library