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E3 Ligase
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Structure Catalog Product Name CAS E3 Ligase Target Inquiry
(2S,4R)-1-((S)-2-(tert-Butyl)-17-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200753 (2S,4R)-1-((S)-2-(tert-Butyl)-17-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461950-62-7

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 Inquiry

Molecular Weight: 1169.39

Molecular Formula: C62H68N6O13S2

Density: 1.33±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-1-((S)-2-(tert-Butyl)-20-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15,18-pentaoxa-3-azaicosanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200754 (2S,4R)-1-((S)-2-(tert-Butyl)-20-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15,18-pentaoxa-3-azaicosanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461951-11-9

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 Inquiry

Molecular Weight: 1213.44

Molecular Formula: C64H72N6O14S2

Density: 1.33±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-1-((S)-2-(tert-Butyl)-23-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15,18,21-hexaoxa-3-azatricosanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200755 (2S,4R)-1-((S)-2-(tert-Butyl)-23-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15,18,21-hexaoxa-3-azatricosanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461951-64-2

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 Inquiry

Molecular Weight: 1257.49

Molecular Formula: C66H76N6O15S2

Density: 1.32±0.1 g/cm3

Description: It is a potent ER degrader.
N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-2-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)acetamide BPL-200756 N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-2-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)acetamide 2461952-23-6

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ER

 Inquiry

Molecular Weight: 845.89

Molecular Formula: C47H35N5O9S

Density: 1.44±0.1 g/cm3

Description: It is a potent ER degrader.
N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-4-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)butanamide BPL-200757 N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-4-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)butanamide 2461953-78-4

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ER

 Inquiry

Molecular Weight: 873.94

Molecular Formula: C49H39N5O9S

Density: 1.41±0.1 g/cm3

Description: It is a potent ER degrader.
N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-5-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)pentanamide BPL-200758 N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-5-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)pentanamide 2461954-40-3

CRBN

ER

 Inquiry

Molecular Weight: 887.97

Molecular Formula: C50H41N5O9S

Density: 1.39±0.1 g/cm3

Description: It is a potent ER degrader.
N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-6-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)hexanamide BPL-200759 N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-6-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)hexanamide 2461954-80-1

CRBN

ER

 Inquiry

Molecular Weight: 902.00

Molecular Formula: C51H43N5O9S

Density: 1.38±0.1 g/cm3

Description: It is a potent ER degrader.
N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-7-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)heptanamide BPL-200760 N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-7-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)heptanamide 2461955-44-0

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ER

 Inquiry

Molecular Weight: 916.03

Molecular Formula: C52H45N5O9S

Density: 1.37±0.1 g/cm3

Description: It is a potent ER degrader.
N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-8-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)octanamide BPL-200761 N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-8-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)octanamide 2461956-04-5

CRBN

ER

 Inquiry

Molecular Weight: 930.05

Molecular Formula: C53H47N5O9S

Density: 1.36±0.1 g/cm3

Description: It is a potent ER degrader.
N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-2-(2-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)ethoxy)acetamide BPL-200762 N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-2-(2-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)ethoxy)acetamide 2461956-37-4

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ER

 Inquiry

Molecular Weight: 889.94

Molecular Formula: C49H39N5O10S

Density: 1.42±0.1 g/cm3

Description: It is a potent ER degrader.
N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-2-(2-(2-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)ethoxy)ethoxy)acetamide BPL-200763 N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-2-(2-(2-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)ethoxy)ethoxy)acetamide 2461956-77-2

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ER

 Inquiry

Molecular Weight: 933.98

Molecular Formula: C51H43N5O11S

Density: 1.40±0.1 g/cm3

Description: It is a potent ER degrader.
N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-2-(2-(2-(2-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)ethoxy)ethoxy)ethoxy)acetamide BPL-200764 N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-2-(2-(2-(2-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)ethoxy)ethoxy)ethoxy)acetamide 2461957-65-1

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ER

 Inquiry

Molecular Weight: 978.05

Molecular Formula: C53H47N5O12S

Density: 1.39±0.1 g/cm3

Description: It is a potent ER degrader.
N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-14-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)-3,6,9,12-tetraoxatetradecanamide BPL-200765 N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-14-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)-3,6,9,12-tetraoxatetradecanamide 2461958-09-6

CRBN

ER

 Inquiry

Molecular Weight: 1022.10

Molecular Formula: C55H51N5O13S

Density: 1.37±0.1 g/cm3

Description: It is a potent ER degrader.
N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-17-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)-3,6,9,12,15-pentaoxaheptadecanamide BPL-200766 N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-17-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)-3,6,9,12,15-pentaoxaheptadecanamide 2461958-55-2

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ER

 Inquiry

Molecular Weight: 1066.16

Molecular Formula: C57H55N5O14S

Density: 1.36±0.1 g/cm3

Description: It is a potent ER degrader.
N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-20-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)-3,6,9,12,15,18-hexaoxaicosanamide BPL-200767 N-(3-(2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)prop-2-yn-1-yl)-20-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)-3,6,9,12,15,18-hexaoxaicosanamide 2461959-07-7

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ER

 Inquiry

Molecular Weight: 1110.21

Molecular Formula: C59H59N5O15S

Density: 1.35±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(2-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200768 (2S,4R)-4-Hydroxy-1-((S)-2-(2-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461959-72-6

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ER

 Inquiry

Molecular Weight: 965.17

Molecular Formula: C53H52N6O8S2

Density: 1.36±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(4-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)butanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200769 (2S,4R)-4-Hydroxy-1-((S)-2-(4-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)butanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461960-52-9

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ER

 Inquiry

Molecular Weight: 993.22

Molecular Formula: C55H56N6O8S2

Density: 1.34±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(5-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)pentanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200770 (2S,4R)-4-Hydroxy-1-((S)-2-(5-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)pentanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461961-08-8

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ER

 Inquiry

Molecular Weight: 1007.25

Molecular Formula: C56H58N6O8S2

Density: 1.33±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(6-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)hexanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200771 (2S,4R)-4-Hydroxy-1-((S)-2-(6-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)hexanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461961-56-6

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ER

 Inquiry

Molecular Weight: 1021.28

Molecular Formula: C57H60N6O8S2

Density: 1.32±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(7-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)heptanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200772 (2S,4R)-4-Hydroxy-1-((S)-2-(7-(4-((2-(4-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)heptanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461962-09-2

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ER

 Inquiry

Molecular Weight: 1035.30

Molecular Formula: C58H62N6O8S2

Density: 1.31±0.1 g/cm3

Description: It is a potent ER degrader.

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