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E3 Ligase
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Structure Catalog Product Name CAS E3 Ligase Target Inquiry
(2S,4R)-4-Hydroxy-1-((S)-2-(4-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)butanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200793 (2S,4R)-4-Hydroxy-1-((S)-2-(4-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)butanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461981-19-9

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Molecular Weight: 1021.23

Molecular Formula: C56H56N6O9S2

Density: 1.35±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(5-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)pentanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200794 (2S,4R)-4-Hydroxy-1-((S)-2-(5-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)pentanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461981-89-3

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Molecular Weight: 1035.26

Molecular Formula: C57H58N6O9S2

Density: 1.34±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(6-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)hexanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200795 (2S,4R)-4-Hydroxy-1-((S)-2-(6-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)hexanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461982-56-7

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Molecular Weight: 1049.29

Molecular Formula: C58H60N6O9S2

Density: 1.33±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(7-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)heptanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200796 (2S,4R)-4-Hydroxy-1-((S)-2-(7-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)heptanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461983-73-1

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Molecular Weight: 1063.31

Molecular Formula: C59H62N6O9S2

Density: 1.33±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(8-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)octanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200797 (2S,4R)-4-Hydroxy-1-((S)-2-(8-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)octanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461984-37-0

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Molecular Weight: 1077.34

Molecular Formula: C60H64N6O9S2

Density: 1.32±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(2-(2-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200798 (2S,4R)-4-Hydroxy-1-((S)-2-(2-(2-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461984-93-8

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Molecular Weight: 1037.23

Molecular Formula: C56H56N6O10S2

Density: 1.36±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(2-(2-(2-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)ethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200799 (2S,4R)-4-Hydroxy-1-((S)-2-(2-(2-(2-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)ethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461985-81-7

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Molecular Weight: 1081.28

Molecular Formula: C58H60N6O11S2

Density: 1.35±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-1-((S)-2-(tert-Butyl)-14-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12-trioxa-3-azatetradecanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200800 (2S,4R)-1-((S)-2-(tert-Butyl)-14-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12-trioxa-3-azatetradecanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461986-37-6

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 Inquiry

Molecular Weight: 1125.34

Molecular Formula: C60H64N6O12S2

Density: 1.34±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-1-((S)-2-(tert-Butyl)-17-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200801 (2S,4R)-1-((S)-2-(tert-Butyl)-17-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2462039-94-5

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Molecular Weight: 1169.39

Molecular Formula: C62H68N6O13S2

Density: 1.33±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-1-((S)-2-(tert-Butyl)-20-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15,18-pentaoxa-3-azaicosanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200802 (2S,4R)-1-((S)-2-(tert-Butyl)-20-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15,18-pentaoxa-3-azaicosanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461995-48-0

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Molecular Weight: 1213.44

Molecular Formula: C64H72N6O14S2

Density: 1.33±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-1-((S)-2-(tert-Butyl)-23-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15,18,21-hexaoxa-3-azatricosanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200803 (2S,4R)-1-((S)-2-(tert-Butyl)-23-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene-3-carbonyl)benzoyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12,15,18,21-hexaoxa-3-azatricosanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461996-49-4

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Molecular Weight: 1257.49

Molecular Formula: C66H76N6O15S2

Density: 1.32±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(2-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200804 (2S,4R)-4-Hydroxy-1-((S)-2-(2-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461997-00-0

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Molecular Weight: 965.17

Molecular Formula: C53H52N6O8S2

Density: 1.36±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(4-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)butanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200805 (2S,4R)-4-Hydroxy-1-((S)-2-(4-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)butanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461997-42-0

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Molecular Weight: 993.22

Molecular Formula: C55H56N6O8S2

Density: 1.34±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(5-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)pentanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200806 (2S,4R)-4-Hydroxy-1-((S)-2-(5-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)pentanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461997-89-5

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Molecular Weight: 1007.25

Molecular Formula: C56H58N6O8S2

Density: 1.33±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(6-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)hexanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200807 (2S,4R)-4-Hydroxy-1-((S)-2-(6-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)hexanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461998-40-1

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 Inquiry

Molecular Weight: 1021.28

Molecular Formula: C57H60N6O8S2

Density: 1.32±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(7-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)heptanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200808 (2S,4R)-4-Hydroxy-1-((S)-2-(7-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)heptanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461999-40-4

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 Inquiry

Molecular Weight: 1035.30

Molecular Formula: C58H62N6O8S2

Density: 1.31±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(8-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)octanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200809 (2S,4R)-4-Hydroxy-1-((S)-2-(8-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)octanamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2461999-86-8

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Molecular Weight: 1049.33

Molecular Formula: C59H64N6O8S2

Density: 1.30±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(2-(2-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200810 (2S,4R)-4-Hydroxy-1-((S)-2-(2-(2-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2462000-33-3

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Molecular Weight: 1009.22

Molecular Formula: C55H56N6O9S2

Density: 1.35±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-4-Hydroxy-1-((S)-2-(2-(2-(2-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)ethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200811 (2S,4R)-4-Hydroxy-1-((S)-2-(2-(2-(2-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)ethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2462000-82-2

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Molecular Weight: 1053.27

Molecular Formula: C57H60N6O10S2

Density: 1.34±0.1 g/cm3

Description: It is a potent ER degrader.
(2S,4R)-1-((S)-2-(tert-Butyl)-14-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12-trioxa-3-azatetradecanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide BPL-200812 (2S,4R)-1-((S)-2-(tert-Butyl)-14-(4-((2-(3-(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)benzoyl)hydrazineylidene)methyl)phenoxy)-4-oxo-6,9,12-trioxa-3-azatetradecanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2462001-51-8

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Molecular Weight: 1097.33

Molecular Formula: C59H64N6O11S2

Density: 1.33±0.1 g/cm3

Description: It is a potent ER degrader.

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