Bis-PEG4-acid

 CAS No.: 31127-85-2  Cat No.: BP-500018  Purity: >95% 4.5  

Bis-PEG4-acid is a PEG PROTAC linker. Bis-PEG4-acid is a PEG derivative containing two terminal carboxylic acid groups. The terminal carboxylic acids can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Bis-PEG4-acid

Structure of 31127-85-2

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Category
PROTAC Linker
Molecular Formula
C12H22O8
Molecular Weight
294.30
Appearance
Pale Yellow or Colorless Oily Matter

* For research and manufacturing use only. Not for human or clinical use.

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Purity
>95%
Solubility
Soluble in DCM, DMF, DMSO, Water
Appearance
Pale Yellow or Colorless Oily Matter
Storage
Store at 2-8°C
Shipping
Room temperature in continental US; may vary elsewhere
IUPACName
3-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]ethoxy]propanoic acid
Synonyms
4,7,10,13-Tetraoxahexadecane-1,16-dioic acid; 4,7,10,13-tetraoxahexadecanedioic acid; HOOCCH2CH2O-PEG3-CH2CH2COOH; α,ω-Dipropionic acid triethylene glycol; 4,7,10,13-Tetraoxa-hexadecan-1,16-dicarbonsaeure
Boiling Point
483.7±45.0 °C at 760 mmHg
Density
1.219±0.06 g/cm3 (Predicted)
InChI Key
LGEVPLDBBPWJIC-UHFFFAOYSA-N
InChI
InChI=1S/C12H22O8/c13-11(14)1-3-17-5-7-19-9-10-20-8-6-18-4-2-12(15)16/h1-10H2,(H,13,14)(H,15,16)
Canonical SMILES
C(COCCOCCOCCOCCC(=O)O)C(=O)O

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: INY-03-041 trihydrochloride | Thalidomide-linker 4 | Schisandrin C | Thalidomide-O-amido-C3-COOH | SIM1 | Hydroxy-PEG1-t-butyl ester | Pomalidomide-C6-PEG3-butyl azide | Pomalidomide-C6-COOH | MD-224 | Bis-PEG4-acid

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