Amino-PEG3-propionic acid

 CAS No.: 784105-33-5  Cat No.: BP-500082  Purity: ≥ 97.0 % 4.5  

Amino-PEG3-propionic acid is a short PEG-based ADC linker intermediate, enhancing antibody conjugation efficiency, solubility, and stability. It supports targeted drug delivery by improving payload attachment and linker flexibility in antibody-drug conjugates.

Amino-PEG3-propionic acid

Structure of 784105-33-5

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Category
PROTAC Linker
Molecular Formula
C9H19NO5
Molecular Weight
221.25
Appearance
White powder

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥ 97.0 %
Solubility
10 mm in DMSO
Appearance
White powder
Storage
Store at -20 °C, keep in dry and avoid sunlight.
Shipping
Room temperature
IUPACName
3-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]propanoic acid
Synonyms
3-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)propanoic acid; H2N-PEG3-CH2CH2COOH
Boiling Point
372.1±32.0 °C at 760 mmHg
Density
1.1±0.1 g/cm3
InChI Key
XUQZKSCQPMNDEY-UHFFFAOYSA-N
InChI
InChI=1S/C9H19NO5/c10-2-4-14-6-8-15-7-5-13-3-1-9(11)12/h1-8,10H2,(H,11,12)
Canonical SMILES
C(COCCOCCOCCN)C(=O)O
Biological Activity
Amino-PEG3-C2-acid is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: INY-03-041 trihydrochloride | Thalidomide-linker 4 | Schisandrin C | Thalidomide-O-amido-C3-COOH | SIM1 | Hydroxy-PEG1-t-butyl ester | Pomalidomide-C6-PEG3-butyl azide | Pomalidomide-C6-COOH | MD-224 | Bis-PEG4-acid | Amino-PEG3-propionic acid

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