DBCO-PEG5-acid

 CAS No.: 1870899-46-9  Cat No.: BP-501000  Purity: >98.0% 4.5  

DBCO-PEG5-acid is a DBCO-terminated PEG linker ideal for azide-reactive SPAAC conjugation in antibody-drug conjugates. It supports site-specific, copper-free click chemistry, enhancing payload attachment and maintaining ADC stability in physiological environments.

DBCO-PEG5-acid

Structure of 1870899-46-9

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Category
PROTAC Linker
Molecular Formula
C32H40N2O9
Molecular Weight
596.67
Appearance
Solid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
>98.0%
Solubility
10 mm in DMSO
Appearance
Solid
ShelfLife
≥ 2 years
Storage
Store at -5°C,keep in dry and avoid sunlight.
Shipping
Room temperature, or blue ice upon request.
IUPACName
3-[2-[2-[2-[2-[3-[[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Synonyms
DBCO-NHCO-PEG4-acid; 3-[2-[2-[2-[2-[3-[[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid; DBCO-Amide-PEG5-acid
InChI Key
IBWIRDQMNBYUPH-UHFFFAOYSA-N
InChI
InChI=1S/C32H40N2O9/c35-30(12-15-39-17-19-41-21-23-43-24-22-42-20-18-40-16-13-32(37)38)33-14-11-31(36)34-25-28-7-2-1-5-26(28)9-10-27-6-3-4-8-29(27)34/h1-8H,11-25H2,(H,33,35)(H,37,38)
Canonical SMILES
C1C2=CC=CC=C2C#CC3=CC=CC=C3N1C(=O)CCNC(=O)CCOCCOCCOCCOCCOCCC(=O)O

Stock concentration: *
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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
g

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