Mal-PEG1-PFP ester

 CAS No.: 1807530-08-0  Cat No.: BP-500348  Purity: ≥95% 4.5  

Mal-PEG1-PFP ester is a PEG linker containing maleimide and PFP moieties. Maleimide is thiol-reactive and reacts between pH 6.5 and 7.5 to form thiol ester bonds. PFP moiety is amine-reactive and is less susceptible to undergoing hydrolysis. The hydrophilic PEG linker increases the water solubility of a compound in aqueous media.

Mal-PEG1-PFP ester

Structure of 1807530-08-0

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PROTAC Linker
Molecular Formula
C15H10F5NO5
Molecular Weight
379.24

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DCM, DMSO
Storage
Store at 2-8°C
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
(2,3,4,5,6-pentafluorophenyl) 3-[2-(2,5-dioxopyrrol-1-yl)ethoxy]propanoate
Synonyms
Mal-PEG1-PFP; Perfluorophenyl 3-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)propanoate; Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester
Boiling Point
452.8±45.0°C at 760 mmHg
Density
1.5±0.1 g/cm3
InChI Key
ZKWVOGYIIBUFNC-UHFFFAOYSA-N
InChI
InChI=1S/C15H10F5NO5/c16-10-11(17)13(19)15(14(20)12(10)18)26-9(24)3-5-25-6-4-21-7(22)1-2-8(21)23/h1-2H,3-6H2
Canonical SMILES
C1=CC(=O)N(C1=O)CCOCCC(=O)OC2=C(C(=C(C(=C2F)F)F)F)F

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Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: 1-Isothiocyanato-PEG4-alcohol | t-Butoxycarbonyl-PEG4-NHS ester | Bis-PEG2-PFP ester | mPEG4-propyne | N-Boc-N-bis(PEG4-OH) | N-(m-PEG9)-N'-(PEG5-acid)-Cy5 | Bis-PEG13-PFP ester | mPEG3-hydrazide | TCO-PEG4-TCO | Sulfo DBCO-amine | Mal-PEG1-PFP ester

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