mPEG6-NHS ester

 CAS No.: 1449390-12-8  Cat No.: BP-500334  Purity: >98.0% 4.5  

mPEG6-NHS ester is a PEG linker with a reactive NHS ester group used for amine coupling in ADC synthesis. The PEG6 spacer increases hydrophilicity, ensuring stable payload conjugation and improved pharmacokinetic behavior of antibody-drug conjugates.

mPEG6-NHS ester

Structure of 1449390-12-8

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Category
PROTAC Linker
Molecular Formula
C18H31NO10
Molecular Weight
421.44
Appearance
Colorless Liquid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
>98.0%
Solubility
10 mm in DMSO
Appearance
Colorless Liquid
ShelfLife
0-4°C for short term (days to weeks), or -20°C for long term (months).
Storage
Store at -20 °C, keep in dry and avoid sunlight.
Shipping
Room temperature
IUPACName
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Synonyms
2,5-dioxopyrrolidin-1-yl 2,5,8,11,14,17-hexaoxaicosan-20-oate
Boiling Point
502.6±60.0 °C at 760 mmHg
Density
1.2±0.1 g/cm3
InChI Key
KIIPLYSZOISNAS-UHFFFAOYSA-N
InChI
InChI=1S/C18H31NO10/c1-23-6-7-25-10-11-27-14-15-28-13-12-26-9-8-24-5-4-18(22)29-19-16(20)2-3-17(19)21/h2-15H2,1H3
Canonical SMILES
COCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O

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Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: Azido-PEG3-S-PEG4-propargyl | 1-Phenyl-2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-yl 4-methylbenzenesulfonate | Boc-gly-PEG3-endo-BCN | Azido-PEG11-azide | Dasatinib carbaldehyde | Hydroxy-PEG2-C2-sulfonic acid | Azido-PEG3-azide | Bromoacetamido-PEG4-t-butyl ester | Propargyl-PEG4-Sulfone-PEG4-Boc | N-Succinimidyl 6-Biotinamidohexanoate | mPEG6-NHS ester

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