N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester

 CAS No.: 2112732-03-1  Cat No.: BP-500976  Purity: 98% 4.5  

N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester is a polyethylene glycol (PEG)-based PROTAC linker. N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester can be used in the synthesis of a series of PROTACs.

N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester

Structure of 2112732-03-1

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PROTAC Linker
Molecular Formula
C₂₆H₅₀N₄O₁₀
Molecular Weight
578.70

* For research and manufacturing use only. Not for human or clinical use.

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Popular Publications Citing BOC Sciences Products
Purity
98%
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
tert-butyl 3-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]ethoxy]ethoxy]ethoxy]propanoate
Synonyms
tert-butyl 3-(2-{2-[2-(16-azido-2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-5-yl)ethoxy]ethoxy}ethoxy)propanoate
InChI Key
IZIWQDDVTKZAPK-UHFFFAOYSA-N
InChI
InChI=1S/C26H50N4O10/c1-25(2,3)39-23(31)7-11-33-15-19-37-21-17-35-13-9-30(24(32)40-26(4,5)6)10-14-36-18-22-38-20-16-34-12-8-28-29-27/h7-22H2,1-6H3
Canonical SMILES
CC(C)(C)OC(=O)CCOCCOCCOCCN(CCOCCOCCOCCN=[N+]=[N-])C(=O)OC(C)(C)C
1. Notch Signaling Mediates Radiation-Induced Smooth Muscle Cell Hypermuscularization and Cerebral Vasculopathy
Yuhua Yang, Honghong Li, Yongteng Xu, Jiatian Xie, Qiang Liu, Zhongshan Shi, Jialin Huang, Jinping Cheng, Siqi Chen, Sitai Chen, Xiaohui Zhao, Shaojian Li, Zhan Zhang, Jinhua Cai, Baixuan He, Wei-Jye Lin, Qingyu Shen, Yi Li, Yamei Tang Stroke. 2022 Dec;53(12):3751-3762.doi: 10.1161/STROKEAHA.122.040697.Epub 2022 Oct 28.
Background:Emerging evidence highlighted vascular injury in aggravating radiation-induced brain injury (RIBI), a common complication of radiotherapy. This study aimed to delineate the pathological feature of cerebral small vessel and investigate the functional roles of Notch signaling in RIBI.

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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