t-Boc-N-amido-PEG7-propionic acid
Boc-NH-PEG7-acid is a polyethylene glycol (PEG)-based PROTAC linker. Boc-NH-PEG7-acid can be used in the synthesis of a series of PROTACs.
Structure of 2055044-68-1
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Category
PROTAC Linker
Molecular Formula
C22H43NO11
Molecular Weight
497.58
Related CAS
187848-68-6 (polymer)
Appearance
Pale Yellow or Colorless Oily Liquid
* For research and manufacturing use only. Not for human or clinical use.
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Purity
≥95%
Solubility
Soluble in DMSO
Appearance
Pale Yellow or Colorless Oily Liquid
Storage
Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Shipping
Room temperature in continental US; may vary elsewhere.
IUPACName
3-[2-[2-[2-[2-[2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Synonyms
t-Boc-N-amido-PEG7-acid; Boc-NH-PEG7-CH2CH2COOH; t-Boc-NH-amido-PEG7-COOH; Boc-NH-PEG7-COOH; 5,8,11,14,17,20,23-Heptaoxa-2-azahexacosanedioic Acid 1-(1,1-Dimethylethyl) Ester; 2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23,26-octaoxa-5-azanonacosan-29-oic acid; 3,8,11,14,17,20,23,26-Octaoxa-5-azanonacosan-29-oic acid, 2,2-dimethyl-4-oxo-
Boiling Point
598.4±50.0 °C at 760 mmHg
Density
1.122±0.06 g/cm3 (Predicted)
InChI Key
NRLJITQFPLHTDR-UHFFFAOYSA-N
InChI
InChI=1S/C22H43NO11/c1-22(2,3)34-21(26)23-5-7-28-9-11-30-13-15-32-17-19-33-18-16-31-14-12-29-10-8-27-6-4-20(24)25/h4-19H2,1-3H3,(H,23,26)(H,24,25)
SMILES
CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCC(=O)O
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
Historical Records: Maleimido-tri(ethylene glycol)-propionic acid | 1-Acetyloxy-2,5-dioxopyrrolidine-3-sulfonic acid | tert-Butyl 3-aminopropanoate | Protein degrader 1 hydrochloride | 2-(2,6-Dioxopiperidin-3-yl)-4-((9-hydroxynonyl)oxy)isoindoline-1,3-dione | (S,R,S)-AHPC-PEG2-NH2 dihydrochloride | PND-1186 (VS-4718) | (S,R,S)-AHPC-C3-NH2 | N-(Azido-PEG4)-biocytin | t-Boc-N-amido-PEG1-acetic acid | t-Boc-N-amido-PEG7-propionic acid
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