(S,R,S)-AHPC-CO-C6-COOH

 CAS No.: 2172819-75-7  Cat No.: BP-100149 4.5  

(S,R,S)-AHPC-CO-C6-COOH is a VHL ligand with a linker, which is a useful precursor for synthesis of VHL ligand based PROTAC (proteolysis-targeting chimera) protein degrader.

(S,R,S)-AHPC-CO-C6-COOH

Structure of 2172819-75-7

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Category
E3 Ligase Ligand-Linker Conjugate
Molecular Formula
C30H42N4O6S
Molecular Weight
586.75

* For research and manufacturing use only. Not for human or clinical use.

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Popular Publications Citing BOC Sciences Products
IUPACName
8-[[(2S)-1-[(2S,4R)-4-hydroxy-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]amino]-8-oxooctanoic acid
Synonyms
VH 032 amide-alkylC6-acid; (S,R,S)-AHPC-amido-C6-acid
InChI Key
DCNOFAZZHMWMEI-QSEAXJEQSA-N
InChI
InChI=1S/C30H42N4O6S/c1-19-26(41-18-32-19)21-13-11-20(12-14-21)16-31-28(39)23-15-22(35)17-34(23)29(40)27(30(2,3)4)33-24(36)9-7-5-6-8-10-25(37)38/h11-14,18,22-23,27,35H,5-10,15-17H2,1-4H3,(H,31,39)(H,33,36)(H,37,38)/t22-,23+,27-/m1/s1
Canonical SMILES
CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)NC(=O)CCCCCCC(=O)O)O

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Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
g/mol
g
Historical Records: (S,R,S)-AHPC-C8-NH2 | (S,R,S)-AHPC-C6-NH2 | VH 032 Linker 3 | Pomalidomide-PEG2-Alkyne | (S,R,S)-AHPC-PEG3-N3 | (S,R,S)-AHPC-CO-PEG1-COOH | Pomalidomide-PEG3-Alkyne | (S,R,S)-AHPC-CO-C2-ACID | Pomalidomide-PEG5-Alkyne | Pomalidomide-PEG1-Alkyne | (S,R,S)-AHPC-CO-C6-COOH

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