t-Boc-N-amido-PEG5-amine

 CAS No.: 189209-27-6  Cat No.: BP-500014  Purity: ≥95% 4.5  

NH2-PEG5-C2-NH-Boc is a PROTAC linker, which refers to the alkyl/ether composition. NH2-PEG5-C2-NH-Boc can be used in the synthesis of a series of PROTACs. NH2-PEG5-C2-NH-Boc is a PEG derivative containing an amino group and Boc-protected amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.

t-Boc-N-amido-PEG5-amine

Structure of 189209-27-6

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Category
PROTAC Linker
Molecular Formula
C17H36N2O7
Molecular Weight
380.48
Appearance
Pale Yellow or Colorless Oily Matter

* For research and manufacturing use only. Not for human or clinical use.

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Purity
≥95%
Solubility
Soluble in DCM, DMF, DMSO, Water
Appearance
Pale Yellow or Colorless Oily Matter
Storage
Store at 2-8°C, protect from light
Shipping
Room temperature in continental US; may vary elsewhere
IUPACName
tert-butyl N-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
Synonyms
NHBoc-PEG5-amine; O-(2-Aminoethyl)-O'-[2-(Boc-amino)ethyl]tetraethylene Glycol; 19-Amino-5,8,11,14,17-pentaoxa-2-azanonadecanoic Acid 1,1-Dimethylethyl Ester; Boc-NH-PEG5-CH2CH2NH2; tert-butyl (17-amino-3,6,9,12,15-pentaoxaheptadecyl)carbamate; NH2-PEG5-C2-NH-Boc; Boc-N-amido-PEG5-Amine; N1-Boc-3,6,9,12,15-pentaoxaheptadecane-1,17-diamine; 5,8,11,14,17-Pentaoxa-2-azanonadecanoic acid, 19-amino-, 1,1-dimethylethyl ester; N-(t-butyloxycarbonyl)-3,6,9,12,15-pentaoxaheptadecane-1,17-diamine; Carbamic acid, N-(17-amino-3,6,9,12,15-pentaoxaheptadec-1-yl)-, 1,1-dimethylethyl ester
Boiling Point
480.2±45.0 °C at 760 mmHg
Density
1.1±0.1 g/cm3
InChI Key
ASGHPQVHGBCLDZ-UHFFFAOYSA-N
InChI
InChI=1S/C17H36N2O7/c1-17(2,3)26-16(20)19-5-7-22-9-11-24-13-15-25-14-12-23-10-8-21-6-4-18/h4-15,18H2,1-3H3,(H,19,20)
Canonical SMILES
CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCN

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It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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