Tetraethylene glycol monotosylate

 CAS No.: 77544-60-6  Cat No.: BP-501357  Purity: > 98.0 % 4.5  

Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Tetraethylene glycol monotosylate

Structure of 77544-60-6

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Category
PROTAC Linker
Molecular Formula
C15H24O7S
Molecular Weight
348.41
Appearance
Colourless to light (or pale) yellow liquid

* For research and manufacturing use only. Not for human or clinical use.

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Purity
> 98.0 %
Solubility
10 mm in DMSO
Appearance
Colourless to light (or pale) yellow liquid
Storage
-20 °C
Shipping
-20°C (International: -20°C)
IUPACName
2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
Synonyms
Tos-PEG4; Tos-PEG4-OH; Tetraethyleneglycol monotosylate; 2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]ethyl tosylate
InChI Key
FGDJUEZBMFELRW-UHFFFAOYSA-N
InChI
InChI=1S/C15H24O7S/c1-14-2-4-15(5-3-14)23(17,18)22-13-12-21-11-10-20-9-8-19-7-6-16/h2-5,16H,6-13H2,1H3
Canonical SMILES
CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOCCOCCO

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L

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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* Total Molecular Weight:
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Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
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Historical Records: Fmoc-N-amido-PEG8-acetic acid | Benzyl-PEG6-amine | THP-PEG8-alcohol | Hydroxy-PEG4-acetic acid | Chloroacetamido-PEG4-NHS ester | Amino-PEG7-amine | Amino-PEG3-C2-sulfonic acid | Amino-PEG9-amine | Tr-PEG4-OH | Azido-PEG10-alcohol | Tetraethylene glycol monotosylate

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