THP-PEG6-alcohol - CAS 42607-87-4

THP-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. THP-PEG6-OH is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

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Molecular Formula
C17H34O8
Molecular Weight
366.45

THP-PEG6-alcohol

    • Specification
      • Related CAS
        92417-25-9 (polymer) 301295-36-3 (polymer)
        Purity
        ≥95%
        Solubility
        Soluble in DMSO (10 mm)
        Appearance
        Solid
        Shelf Life
        -20°C 3 years powder; -80°C 2 years in solvent
        Storage
        Store at 2-8°C
        Shipping
        -20°C (International: -20°C)
        IUPAC Name
        2-[2-[2-[2-[2-[2-(oxan-2-yloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
        Synonyms
        OH-PEG6-THP; HO-PEG6-THP; THP-PEG7; THP-PEG6-OH; 3,6,9,12,15-Pentaoxaheptadecan-1-ol, 17-[(tetrahydro-2H-pyran-2-yl)oxy]-; 17-((Tetrahydro-2H-pyran-2-yl)oxy)-3,6,9,12,15-pentaoxaheptadecan-1-ol
    • Properties
      • Boiling Point
        469.0±45.0 °C at 760 mmHg
        Density
        1.10±0.1 g/cm3 (Predicted)
        InChI Key
        ABJWCLPYMPRGRB-UHFFFAOYSA-N
        InChI
        InChI=1S/C17H34O8/c18-4-6-19-7-8-20-9-10-21-11-12-22-13-14-23-15-16-25-17-3-1-2-5-24-17/h17-18H,1-16H2
        Canonical SMILES
        C1CCOC(C1)OCCOCCOCCOCCOCCOCCO
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