Name: TYK2-IN-2
Brand: BOC Sciences
Rating: 5 (1 reviews)

Size

Price

Stock

Quantity

$--

In stock

Solubility

DMSO: ≥ 25 mg/mL

Storage

Store in a cool and dry place (or refer to the Certificate of Analysis).

IUPACName

6-(3,5-dimethylanilino)-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide

Synonyms

6-(3,5-dimethylanilino)-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide

Density

1.37±0.1 g/cm3

InChI Key

SNVFFECYFQEWTL-UHFFFAOYSA-N

InChI

1S/C16H18N6O/c1-9-4-10(2)6-11(5-9)20-14-7-12(18-3)16-19-8-13(15(17)23)22(16)21-14/h4-8,18H,1-3H3,(H2,17,23)(H,20,21)

Canonical SMILES

CC1=CC(=CC(=C1)NC2=NN3C(=CN=C3C(=C2)NC)C(=O)N)C

Dear sir, what is the mechanism of action of TYK2-IN-2? thanks a lot.

TYK2-IN-2 works by competitively binding to the ATP-binding site of TYK2. This prevents TYK2 from phosphorylating and activating STAT proteins, which are transcription factors that regulate the expression of genes involved in cell growth, differentiation, and apoptosis. By inhibiting JAK/STAT signaling, TYK2-IN-2 can suppress the proliferation and survival of T cells. This makes it a potential therapeutic agent for a variety of T cell-mediated diseases, such as autoimmune diseases, inflammatory diseases, and cancer.

24/3/2021

How is the solubility of this compound? thanks.

It is also soluble in a variety of organic solvents, such as DMSO and ethanol.

22/3/2023

Stock concentration: *

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* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C₁V₁ = C₂V₂