VL285

 CAS No.: 1448188-57-5  Cat No.: BP-200013 4.5  

VL285 is a potent VHL ligand, degrading HaloTag7 fusion proteins.

VL285

Structure of 1448188-57-5

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Ligand for E3 Ligase
Molecular Formula
C29H32N4O4S
Molecular Weight
532.65

* For research and manufacturing use only. Not for human or clinical use.

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Solubility
DMSO : 125 mg/mL (ultrasonic)
Storage
Powder<br/>-20°C<br/>3 years<br/><br/> <br/> <br/>4°C<br/>2 years<br/><br/><br/>In solvent<br/>-80°C<br/>6 months<br/><br/><br/> <br/>-20°C<br/>1 month
Shipping
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Synonyms
VL-285; VL 285; VL285; 4-hydroxy-1-[3-methyl-2-(3-oxo-1H-isoindol-2-yl)butanoyl]-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
InChI Key
HEDFFPYRFJKXQP-UHFFFAOYSA-N
InChI
InChI=1S/C29H32N4O4S/c1-17(2)25(33-14-21-6-4-5-7-23(21)28(33)36)29(37)32-15-22(34)12-24(32)27(35)30-13-19-8-10-20(11-9-19)26-18(3)31-16-38-26/h4-11,16-17,22,24-25,34H,12-15H2,1-3H3,(H,30,35)
Canonical SMILES
CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)C)N4CC5=CC=CC=C5C4=O)O

Stock concentration: *
Desired final volume: *
Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

Calculate
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
g/mol
g
Historical Records: BI-3802 | PROTAC BRD4 Degrader-2 | Mivebresib | LC-2 | Aminooxy-PEG1-propargyl | PROTAC BRD4 Degrader-1 | SNIPER(ABL)-044 | 3-(4-methoxy-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione | (S,S,S)-AHPC hydrochloride | E3 ligase Ligand 14 | VL285

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